Hashimoto's Thyroiditis Minimizes Lymph Node Metastasis in BRAF Mutant Papillary Thyroid Carcinomas

PP Issa, M Omar, Y Buti, CP Issa, B Chabot… - Biomedicines, 2022 - mdpi.com
Hashimoto's thyroiditis (HT)(autoimmune thyroiditis) is a clinicopathological entity
associated with chronic lymphocytic infiltration resulting in hypothyroidism. HT is a double …

Prevalence and Impact of BRAF mutation in patients with concomitant papillary thyroid carcinoma and Hashimoto's thyroiditis: a systematic review with meta-analysis

L Janicki, A Patel, J Jendrzejewski… - Frontiers in …, 2023 - frontiersin.org
Background Evidence suggests that patients with Hashimoto thyroiditis (HT) are at
significantly higher risk of developing papillary thyroid cancer (PTC). However, the course of …

Effect and Interactions of BRAF on Lymph Node Metastasis in Papillary Thyroid Carcinoma With Hashimoto Thyroiditis

P Li, Y Liu, T Wei, X Wang, J Zhu, R Yang… - The Journal of …, 2024 - academic.oup.com
Context The role of B-Raf proto-oncogene (BRAF) in papillary thyroid carcinoma (PTC) with
Hashimoto thyroiditis (HT) is unknown. Objective We aimed to explore risk factors affecting …

Hashimoto's thyroiditis: A protective factor against recurrence in BRAF-wild type differentiated thyroid carcinoma

PP Issa, M Omar, Y Buti, M Aboueisha, R Munshi… - Cancers, 2023 - mdpi.com
Simple Summary Hashimoto's thyroiditis and BRAF-mutation are protective and risk factors
for thyroid cancer aggressiveness, respectively. We assessed the influence of Hashimoto's …

The Association between Lymphocytic Thyroiditis and Papillary Thyroid Cancer Harboring Mutant BRAF: A Systematic Review and Meta-Analysis

S Perampalam, K Wu, M Gild, L Tacon, M Bullock… - Thyroid, 2024 - liebertpub.com
Background: Papillary thyroid cancer (PTC) and lymphocytic thyroiditis (LT) co-occur with a
prevalence of about 30%. PTC harboring BRAFV600E (PTC-BRAF) confers a worse …

BRAF mutation positive papillary thyroid carcinoma is less advanced when Hashimoto's thyroiditis lymphocytic infiltration is present

V Marotta, A Guerra, MC Zatelli, ED Uberti… - Clinical …, 2013 - Wiley Online Library
Background Concomitant papillary thyroid cancer (PTC) and H ashimoto's thyroiditis (HT) is
a frequent occurrence. Whether these two conditions are linked and whether PTC with …

BRAF V600E mutation and Its Association with Clinicopathological Features of Papillary Thyroid Cancer: A Meta-Analysis

C Li, KC Lee, EB Schneider… - The Journal of Clinical …, 2012 - academic.oup.com
Background: There is conflicting literature regarding the association of the BRAF V600E
mutation and aggressive clinicopathological features of papillary thyroid cancer (PTC) …

Does BRAF V600E Mutation Predict Aggressive Features in Papillary Thyroid Cancer? Results From Four Endocrine Surgery Centers

C Li, P Aragon Han, KC Lee, LC Lee… - The Journal of …, 2013 - academic.oup.com
Background: Existing evidence is controversial regarding the association between BRAF
mutation status and aggressive features of papillary thyroid cancer (PTC). Specifically, no …

BRAF V600E and lymph node metastases in papillary thyroid cancer

P Chen, L Pan, W Huang, H Feng… - Endocrine …, 2020 - ec.bioscientifica.com
Objective: To evaluate the relationship between the BRAF V600E mutation in lymph node
metastasis (LNM) and its invasive characteristics in papillary thyroid cancer (PTC). Material …

Does papillary thyroid carcinoma have a better prognosis with or without Hashimoto thyroiditis?

HY Kwak, BJ Chae, YH Eom, YR Hong, JB Seo… - International journal of …, 2015 - Springer
Background It has been reported that the BRAF V600E mutation is related to a low
frequency of background Hashimoto thyroiditis (HT); however, there are not many factors …