In recent years, there have been major advances in the development of novel nanoparticle-
and microparticle-based therapeutics. An emerging paradigm is the incorporation of …

The engineering of future generations of nanodelivery systems aims at the creation of
multifunctional vectors endowed with improved circulation, enhanced targeting and …

Nanoengineered particles that can facilitate drug formulation and passively target tumors
have reached the clinic in recent years. These early successes have driven a new wave of …

Engineered nanoparticles have the potential to revolutionize the diagnosis and treatment of
many diseases; for example, by allowing the targeted delivery of a drug to particular subsets …

Nanotechnology is an emerging applied science delivering crucial human interventions.
Biogenic nanoparticles produced from natural sources have received attraction in recent …

Nanoparticles can be engineered with distinctive composition, size, shape, and surface
chemistry to enable novel techniques in a wide range of biological applications. The unique …

Highlights•Biological interactions on the nanoscale are critical for the in vivo performance of
nanoparticles.•A central challenge is the reduction of nonspecific interactions while …

The immune system can be a cure or cause of disease, fulfilling a protective role in attacking
cancer or pathogenic microbes but also causing tissue destruction in autoimmune disorders …

Engineered nanoparticles (NPs) play an increasingly important role in biomedical sciences
and in nanomedicine. Yet, in spite of significant advances, it remains difficult to construct …

Advanced treatments based on immune system manipulation, gene transcription and
regulation, specific organ and cell targeting, and/or photon energy conversion have …