The use of angiotensin-converting enzyme inhibitors vs. angiotensin receptor blockers and cognitive decline in Alzheimer's disease: the importance of blood-brain …

M Ouk, CY Wu, JS Rabin, A Jackson… - Alzheimer's Research & …, 2021 - Springer
Background The antihypertensive angiotensin receptor blockers (ARBs) and angiotensin-
converting enzyme inhibitors (ACE-Is) have similar indications and mechanisms of action …

Can angiotensin-converting enzyme inhibitors impact cognitive decline in early stages of Alzheimer's disease? An overview of research evidence in the elderly patient …

K Rygiel - Journal of postgraduate medicine, 2016 - journals.lww.com
Alzheimer's disease (AD) is a neurodegenerative disease, in which an accumulation of toxic
amyloid beta in the brain precedes the emergence of clinical symptoms. AD spectrum …

Neuroprotective effect of angiotensin II receptor blockers on the risk of incident Alzheimer's disease: A nationwide population-based cohort study

HW Lee, S Kim, Y Jo, Y Kim, BS Ye… - Frontiers in Aging …, 2023 - frontiersin.org
Background Recent studies on renin-angiotensin system (RAS) inhibitors have reported a
reduced risk of Alzheimer's disease (AD). Nevertheless, the effect of RAS inhibitor type and …

Associations between brain amyloid accumulation and the use of angiotensin-converting enzyme inhibitors versus angiotensin receptor blockers

M Ouk, CY Wu, JS Rabin, JD Edwards, J Ramirez… - Neurobiology of …, 2021 - Elsevier
Some studies suggest that angiotensin II type 1 receptor blockers (ARBs) may protect
against memory decline more than angiotensin-converting enzyme inhibitors (ACE-Is), but …

Angiotensin converting enzyme inhibitors and cognitive and functional decline in patients with Alzheimer's disease: an observational study

IM Hajjar, M Keown, P Lewis… - American Journal of …, 2008 - journals.sagepub.com
We previously reported that angiotensin converting enzyme inhibitors (ACEIs) decrease the
rate of cognitive decline in elderly patients with hypertension, but their impact on patients …

Angiotensin converting enzyme inhibitors and Alzheimer disease in the presence of the apolipoprotein E4 allele

WWQ Qiu, A Lai, T Mon, M Mwamburi, W Taylor… - The American Journal of …, 2014 - Elsevier
Objective The effect of angiotensin converting enzyme (ACE) inhibitors on Alzheimer
disease (AD) remains unclear, with conflicting results reported. We studied the interaction of …

Memory is preserved in older adults taking AT1 receptor blockers

JK Ho, DA Nation… - Alzheimer's research & …, 2017 - Springer
Background Prior work suggests that some but not all antihypertensive treatments may
benefit cognition and risk for Alzheimer's disease, independent of stroke. Angiotensin II …

Effects of centrally acting angiotensin converting enzyme inhibitors on functional decline in patients with Alzheimer's disease

R O'Caoimh, L Healy, Y Gao… - Journal of …, 2014 - content.iospress.com
Background: Centrally acting angiotensin converting enzyme inhibitors (CACE-Is) are
associated with reduced rates of cognitive decline in patients with dementia. CACE-Is may …

The association of renin-angiotensin system blockade use with the risks of cognitive impairment of aging and Alzheimer's disease: A meta-analysis

S Zhuang, HF Wang, X Wang, J Li, CM Xing - Journal of Clinical …, 2016 - Elsevier
A quantitative meta-analysis was performed to evaluate the association of renin-angiotensin
system blockade (RASB) use with the incidence of cognitive impairment of aging and …

Angiotensin receptor blockers are associated with a lower risk of progression from mild cognitive impairment to dementia

Z Deng, J Jiang, J Wang, D Pan, Y Zhu, H Li… - …, 2022 - Am Heart Assoc
Background: Previous studies found that antihypertensive medications (AHMs) acting on the
renin-angiotensin system had the potential to reduce the progression from mild cognitive …