Role of acute exacerbations in skeletal muscle impairment in COPD

HR Gosker, RC Langen, SO Simons - Expert Review of Respiratory …, 2021 - Taylor & Francis
Introduction: Muscle impairments are prevalent in COPD and have adverse clinical
implications in terms of physical performance capacity, disease burden, quality of life and …

Deterioration of limb muscle function during acute exacerbation of chronic obstructive pulmonary disease

RM Abdulai, TJ Jensen, NR Patel… - American Journal of …, 2018 - atsjournals.org
Important features of both stable and acute exacerbation of chronic obstructive pulmonary
disease (COPD) are skeletal muscle weakness and wasting. Limb muscle dysfunction …

Mechanisms of striated muscle dysfunction during acute exacerbations of COPD

G Gayan-Ramirez, M Decramer - Journal of Applied …, 2013 - journals.physiology.org
During acute exacerbations of chronic obstructive pulmonary disease (COPD), limb and
respiratory muscle dysfunction develops rapidly and functional recovery is partial and slow …

Skeletal muscle dysfunction in COPD: relevance of nutritional support and pulmonary rehabilitation

E Barreiro, A Jaitovich - Journal of Thoracic Disease, 2018 - ncbi.nlm.nih.gov
In this focused issue titled “Nutritional status and muscle dysfunction in chronic obstructive
pulmonary disease: stable versus acute exacerbations”, several review articles have been …

Global muscle dysfunction and exacerbation of COPD: a cohort study

JM Martínez-Llorens, M Orozco-Levi, MJ Masdeu… - Medicina …, 2004 - europepmc.org
BACKGROUND AND OBJECTIVE: The purpose of this study was to evaluate on a
prospective fashion the effects of clinical relapses of chronic obstructive pulmonary disease …

[HTML][HTML] Global muscle dysfunction as a risk factor of readmission to hospital due to COPD exacerbations

J Vilaró, A Ramirez-Sarmiento, JM Martínez-Llorens… - Respiratory …, 2010 - Elsevier
Exacerbations of chronic obstructive pulmonary disease (COPD) are associated with several
modifiable (sedentary life-style, smoking, malnutrition, hypoxemia) and non-modifiable (age …

From muscle disuse to myopathy in COPD: potential contribution of oxidative stress

A Couillard, C Prefaut - European Respiratory Journal, 2005 - Eur Respiratory Soc
Evidence has been accumulating that chronic inactivity leading to muscle disuse is unlikely
to be the only explanation for the peripheral muscle dysfunction of chronic obstructive …

Factors contributing to muscle wasting and dysfunction in COPD patients

RCI Wüst, H Degens - International journal of chronic obstructive …, 2007 - Taylor & Francis
Many patients with chronic obstructive pulmonary disease (COPD) suffer from exercise
intolerance. In about 40% of the patients exercise capacity is limited by alterations in skeletal …

Muscle function in COPD: a complex interplay

AV Donaldson, M Maddocks, D Martolini… - … journal of chronic …, 2012 - Taylor & Francis
The skeletal muscles play an essential role in life, providing the mechanical basis for
respiration and movement. Skeletal muscle dysfunction is prevalent in all stages of chronic …

Skeletal muscles in chronic obstructive pulmonary disease: deconditioning, or myopathy?

PD Wagner - Respirology, 2006 - Wiley Online Library
In recent years, COPD has become increasingly thought of as a systemic disease affecting
many tissues and organs in addition to the lungs. The skeletal muscles in particular have …