[HTML][HTML] Analysis of the intestinal lumen microbiota in an animal model of colorectal cancer

Q Zhu, Z Jin, W Wu, R Gao, B Guo, Z Gao, Y Yang… - PloS one, 2014 - journals.plos.org
Recent reports have suggested that multiple factors such as host genetics, environment and
diet can promote the progression of healthy mucosa towards sporadic colorectal carcinoma …

[HTML][HTML] Impact of microbiota in colorectal carcinogenesis: lessons from experimental models

LCH Yu, SC Wei, YH Ni - Intestinal research, 2018 - ncbi.nlm.nih.gov
A role of gut microbiota in colorectal cancer (CRC) growth was first suggested in germ-free
rats almost 50 years ago, and the existence of disease-associated bacteria (termed …

[HTML][HTML] Structure of the gut microbiome following colonization with human feces determines colonic tumor burden

NT Baxter, JP Zackular, GY Chen, PD Schloss - Microbiome, 2014 - Springer
Background A growing body of evidence indicates that the gut microbiome plays a role in
the development of colorectal cancer (CRC). Patients with CRC harbor gut microbiomes that …

The gut microbiome modulates colon tumorigenesis

JP Zackular, NT Baxter, KD Iverson, WD Sadler… - MBio, 2013 - Am Soc Microbiol
Recent studies have shown that individuals with colorectal cancer have an altered gut
microbiome compared to healthy controls. It remains unclear whether these differences are …

Manipulation of the gut microbiota reveals role in colon tumorigenesis

JP Zackular, NT Baxter, GY Chen, PD Schloss - MSphere, 2016 - Am Soc Microbiol
There is growing evidence that individuals with colonic adenomas and carcinomas harbor a
distinct microbiota. Alterations to the gut microbiota may allow the outgrowth of bacterial …

[HTML][HTML] Differential susceptibility to colorectal cancer due to naturally occurring gut microbiota

AC Ericsson, S Akter, MM Hanson, SB Busi… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Recent studies investigating the human microbiome have identified particular bacterial
species that correlate with the presence of colorectal cancer. To evaluate the role of …

[HTML][HTML] Human intestinal lumen and mucosa-associated microbiota in patients with colorectal cancer

W Chen, F Liu, Z Ling, X Tong, C Xiang - PloS one, 2012 - journals.plos.org
Recent reports have suggested the involvement of gut microbiota in the progression of
colorectal cancer (CRC). We utilized pyrosequencing based analysis of 16S rRNA genes to …

Microbial mucosal colonic shifts associated with the development of colorectal cancer reveal the presence of different bacterial and archaeal biomarkers

L Mira-Pascual, R Cabrera-Rubio, S Ocon… - Journal of …, 2015 - Springer
Background Epidemiological studies demonstrate a link between gastrointestinal cancers
and environmental factors such as diet. It has been suggested that environmental cancer …

Human gut microbiome and risk for colorectal cancer

J Ahn, R Sinha, Z Pei, C Dominianni… - Journal of the …, 2013 - academic.oup.com
We tested the hypothesis that an altered community of gut microbes is associated with risk of
colorectal cancer (CRC) in a study of 47 CRC case subjects and 94 control subjects. 16S …

Sporadic colorectal cancer–role of the commensal microbiota

ME Hope, GL Hold, R Kain… - FEMS microbiology …, 2005 - academic.oup.com
There are vast numbers of bacteria present within the human colon that are essential for the
host's well being in terms of nutrition and mucosal immunity. While certain members of the …