Background and Purpose—Brain imaging abnormalities were reported in up to 44% of
children with sickle cell disease (SCD). The prevalence of neuroimaging abnormalities in …

The purpose of the study was to evaluate transcranial Doppler ultrasonography for
identifying cerebrovascular disease in neurologically asymptomatic children and young …

Background. MR angiography (MRA) provides a mechanism for non-invasively studying
blood flow, thus providing a new opportunity to study the intracranial circulation in …

Ischemic stroke is a common and disabling complication of sickle cell disease (Hb SS). Most
infarctions occur in the presence of intracranial stenotic lesions of the large vessels of the …

A systematic review was performed to assess whether cerebral blood flow with different
imaging modalities could identify brain abnormalities in children with sickle cell disease …

Purpose: To compare the results of standardized magnetic resonance imaging (MRI) of the
brain and transcranial Doppler (TCD) ultrasonography of cerebral arteries in school-aged …

The stroke prevention study in sickle cell disease (STOP) demonstrated a 90% reduction in
stroke risk with transfusion among patients with time-averaged mean cerebral blood velocity …

Abstract Changes on Transcranial Doppler (TCD) ultrasonography have been proposed as
significant predictors of cerebrovascular complications in sickle cell disease (SCD) …

Purpose: We evaluated the accuracy of transcranial Doppler (TCD) and magnetic resonance
angiography (MRA) as a screening modality for cerebral infarct in patients with sickle cell …

A prospective study of 58 patients with sickle cell disease (SCD) by transcranial Doppler
sonography (TCD) included both MRI and MRA in patients over 7 years of age and those …