Inflammatory responses play decisive roles at different stages of tumor development,
including initiation, promotion, malignant conversion, invasion, and metastasis. Inflammation …

It has been established that cancer can be promoted and/or exacerbated by inflammation
and infections. Indeed, chronic inflammation orchestrates a tumor-supporting …

Cancer development and its response to therapy are strongly influenced by innate and
adaptive immunity, which either promote or attenuate tumorigenesis and can have opposing …

Inflammation predisposes to the development of cancer and promotes all stages of
tumorigenesis. Cancer cells, as well as surrounding stromal and inflammatory cells, engage …

Inflammation has long been thought to contribute to the development of cancer; however
there is also clear evidence that the immune system can recognize and eliminate cancer …

In many settings, tumor-associated inflammation, supported mainly by innate immune cells,
contributes to tumor growth. Initial innate activation triggers secretion of inflammatory …

The role of the immune system during cancer development is complex involving extensive
reciprocal interactions between genetically altered cells, adaptive and innate immune cells …

Chronic inflammation increases the risk of several cancers, including gastric, colon, and
hepatic cancers. Conversely, tumors, similar to tissue injury, trigger an inflammatory …

Chronic inflammation promotes tumor development, progression, and metastatic
dissemination and causes treatment resistance. The accumulation of genetic alterations and …

Epigenetic disorders such as point mutations in cellular tumor suppressor genes, DNA
methylation and post-translational modifications are needed to transformation of normal …