Quercetin, a naturally non-toxic flavonoid within the safe dose range with antioxidant, anti-
apoptotic and anti-inflammatory properties, plays an important role in the treatment of aging …

The natural polyphenolic compound resveratrol (3, 4, 5-trihydroxy-trans-stilbene) has broad
spectrum health beneficial activities including antioxidant, anti-inflammatory, anti-aging, anti …

Polyphenols are the known group of phytochemicals that essentially consists of phenolic
rings. These are the plant product present in varied fruits and vegetables. These secondary …

Alzheimer's disease (AD) is a progressive and neurodegenerative disorder of the cortex and
hippocampus, which eventually leads to cognitive impairment. Although the etiology of AD …

Studies have shown that diabetes is an important risk factor for cognitive dysfunction, also
called diabetic encephalopathy (DE). Quercetin has been reported to be effective in …

Abstract Sirtuin 3 (Sirt3), a mitochondrial deacetylase, regulates mitochondrial redox
homeostasis and autophagy and is involved in physiological and pathological processes …

Myocardial fibrosis represents the primary pathological change associated with diabetic
cardiomyopathy and heart failure, and it leads to decreased myocardial compliance with …

Aging and various age-related diseases are associated with reductions in melatonin
secretion, proinflammatory changes in the immune system, a deteriorating circadian system …

Sirtuin1 (SIRT1), a type III protein deacetylase, is considered as a novel anti-aging protein
involved in regulation of cellular senescence/aging and inflammation. SIRT1 level and …

Honokiol (poly-phenolic lignan from Magnolia grandiflora) is a Sirtuin-3 (SIRT3) activator
which exhibit antioxidant activity and augment mitochondrial functions in several …