Microglia cells during aging, neurodegeneration and neuroinflammation show different
morphological and transcriptional profiles (related to axonal direction and cell adhesion) …

As we age, a large number of physiological and molecular changes affect the normal
functioning of cells, tissues, and the organism as a whole. One of the main changes is the …

Pathophysiological processes of neurodegenerative diseases are not clearly defined.
However, an important body of evidence points toward the role of various inflammatory …

Microglia constitute the resident immunocompetent cells of the central nervous system.
Although much work has focused on their ability to mount an inflammatory response in …

Microglia represent a specialized population of macrophages-like cells in the central
nervous system (CNS) considered immune sentinels that are capable of orchestrating a …

Cellular senescence and chronic inflammation in response to aging are considered to be
indicators of brain aging; they have a great impact on the aging process and are the main …

The pathophysiological processes involved in neurodegenerative diseases have not been
clearly defined. Nevertheless, a significant aspect of the proof focuses directly on the …

Microglia, the innate immune cells of the brain, are commonly perceived as resident
macrophages of the central nervous system (CNS). This definition, however, requires further …

Microglia cells are the brain counterpart of macrophages and function as the first defense in
the brain. Although they are neuroprotective in the young brain, microglia cells may be …

Microglia, being the resident immune cells of the central nervous system, play an important
role in maintaining tissue homeostasis and contributes towards brain development under …