[HTML][HTML] Immune Responses in Oral Papillomavirus Clearance in the MmuPV1 Mouse Model

SA Brendle, JJ Li, V Walter, TD Schell, M Kozak… - Pathogens, 2023 - mdpi.com
Human papillomavirus (HPV)-induced oropharyngeal cancer now exceeds HPV-induced
cervical cancer, with a noticeable sex bias. Although it is well established that women have …

An infection-based murine model for papillomavirus-associated head and neck cancer

T Wei, D Buehler, E Ward-Shaw, PF Lambert - MBio, 2020 - Am Soc Microbiol
Human papillomavirus (HPV) is the most common sexually transmitted pathogen, and high-
risk HPVs contribute to 5% of human cancers, including 25% of head and neck squamous …

Insights into the role of innate immunity in cervicovaginal papillomavirus infection from studies using gene-deficient mice

C Scagnolari, F Cannella, A Pierangeli… - Journal of …, 2020 - Am Soc Microbiol
We demonstrate that female C57BL/6J mice are susceptible to a transient lower genital tract
infection with MmuPV1 mouse papillomavirus and display focal histopathological …

[HTML][HTML] The mouse papillomavirus infection model

J Hu, NM Cladel, LR Budgeon, KK Balogh… - Viruses, 2017 - mdpi.com
The mouse papillomavirus (MmuPV1) was first reported in 2011 and has since become a
powerful research tool. Through collective efforts from different groups, significant progress …

The Larynx is Protected from Secondary and Vertical Papillomavirus Infection in Immunocompetent Mice

RE King, J Rademacher, ET Ward‐Shaw… - The …, 2024 - Wiley Online Library
Objective Mouse papillomavirus MmuPV1 causes both primary and secondary infections of
the larynx in immunocompromised mice. Understanding lateral and vertical transmission of …

A Novel In Vivo Infection Model To Study Papillomavirus-Mediated Disease of the Female Reproductive Tract

ME Spurgeon, A Uberoi, SM McGregor, T Wei… - MBio, 2019 - Am Soc Microbiol
Papillomaviruses exhibit species-specific tropism, thereby limiting understanding and
research of several aspects of HPV infection and carcinogenesis. The discovery of a murine …

Development of an in vivo infection model to study Mouse papillomavirus-1 (MmuPV1)

A Uberoi, S Yoshida, PF Lambert - Journal of virological methods, 2018 - Elsevier
Preclinical model systems to study multiple features of the papillomavirus life cycle are
extremely valuable tools to aid our understanding of Human Papillomavirus (HPV) biology …

Host defence and persistent human papillomavirus infection

M Stanley - Current Opinion in Virology, 2021 - Elsevier
Highlights•Evasion of innate immune pathways is the hallmark of HPV infection. Innate
immune receptors and signalling pathway cascades are inhibited by HPV early …

Key aspects of papillomavirus infection influence the host cervicovaginal microbiome in a preclinical murine papillomavirus (MmuPV1) infection model

ME Spurgeon, EC Townsend, S Blaine-Sauer… - Mbio, 2024 - Am Soc Microbiol
Human papillomaviruses (HPVs) are the most common sexually transmitted infection in the
United States and are a major etiological agent of cancers in the anogenital tract and oral …

[HTML][HTML] Innate immunity and HPV: friends or foes

RAL Nunes, MG Morale, GÁF Silva, LL Villa, L Termini - Clinics, 2018 - SciELO Brasil
Most human papillomavirus infections are readily cleared by the host immune response.
However, in some individuals, human papillomavirus can establish a persistent infection …