Using a 32‐echo imaging pulse sequence, T2 relaxation decay curves were acquired from
five white‐and six gray‐matter brain structures outlined in 12 normal volunteers. The water …

Multicomponent T2 relaxation imaging can be used to measure signal from water trapped
between myelin bilayers; the ratio of myelin water signal to total water is termed the myelin …

Purpose Myelin water fraction is conventionally measured from the T2 decay curve.
Recently, a steady‐state approach entitled multicomponent‐driven equilibrium single pulse …

The objective of this study was to implement a clinically relevant multi-slice multi-echo
imaging sequence in order to quantify multi-component T2 relaxation times for normal …

Multi-echo T 2 measurements are invaluable in studying brain pathology in multiple
sclerosis (MS). In addition to information about myelin water and total water content, the T 2 …

Background: Measurements of the T 2 decay curve provide estimates of total water content
and myelin water fraction in white matter in-vivo, which may help in understanding the …

T2 weighting is particularly sensitive, but notoriously unspecific, to a wide range of brain
pathologies. However, careful measurement and analysis of the T2 decay curve from brain …

This work is concerned with the accurate quantification of brain water content under routine
clinical conditions. Gelatin solutions of varying water content are first employed as a model …

Visualizing myelin in human brain may help the study of diseases such as multiple sclerosis.
Previous studies based on T1 and T2 relaxation contrast have suggested the presence of a …

Multiexponential T2 relaxation time measurement in the central nervous system shows a
component that originates from water trapped between the lipid bilayers of myelin. This …