Association of estrogen receptor β gene polymorphism with bone mineral density

S Ogawa, T Hosoi, M Shiraki, H Orimo, M Emi… - Biochemical and …, 2000 - Elsevier
Chromosomal mapping of the human estrogen receptor β (ERβ) gene by fluorescence in
situ hybridization (FISH) reveals that ERβ is located at human chromosome 14, region q23 …

Estrogen receptor β gene polymorphisms are associated with higher bone mineral density in premenopausal, but not postmenopausal southern Chinese women

HHL Lau, AYY Ho, KDK Luk, AWC Kung - Bone, 2002 - Elsevier
Bone mineral density (BMD), the main determining risk factor for osteoporotic fractures, has
a strong genetic component. Estrogen and its receptors play a critical role in both skeletal …

Association of estrogen receptor dinucleotide repeat polymorphism with osteoporosis

M Sano, S Inoue, T Hosoi, Y Ouchi, M Emi… - Biochemical and …, 1995 - Elsevier
We investigated the association between dinucleotide (thymine-adenine) repeat
polymorphism lying upstream of human estrogen receptor (ER) gene and bone mineral …

Estrogen receptor gene polymorphism and bone mineral density in postmenopausal Chinese women

EMC Lau, RP Young, V Lam, M Li, J Woo - Bone, 2001 - Elsevier
PvuII and XbaI restriction fragment length polymorphisms (RFLPs) for the estrogen receptor
gene (ERG) and its relation to bone mineral density (BMD) were examined in 454 …

Estrogen receptor α gene polymorphisms and peak bone density in Chinese nuclear families

YJ Qin, H Shen, QR Huang, LJ Zhao… - Journal of Bone and …, 2003 - academic.oup.com
PBD is an important determinant of osteoporotic fractures. Few studies were performed to
search for genes underlying PBD variation in Chinese populations. We tested linkage and/or …

Association of estrogen receptor-α gene polymorphisms with bone mineral density in postmenopausal Korean women

HS Nam, MH Shin, SS Kweon, KS Park… - Journal of bone and …, 2005 - Springer
We examined the potential associations between Pvu II and Xba I polymorphisms in the first
intron of the estrogen receptor alpha (ER-α) gene and bone mineral density (BMD) in a …

Non-association of estrogen receptor genotypes with bone mineral density and bone turnover in Korean pre-, peri-, and postmenopausal women

K Han, J Choi, I Moon, H Yoon, I Han, H Min… - Osteoporosis …, 1999 - Springer
Estrogen is known to play a critical role in both skeletal maturity and the rate of bone loss.
This suggests the possibility that the estrogen receptor (ER) gene is one of the candidate …

Estrogen receptor α gene polymorphisms and bone mineral density: haplotype analysis in women from the United Kingdom

OME Albagha, FEA McGuigan, DM Reid… - Journal of Bone and …, 2001 - academic.oup.com
Genetic factors are important in the pathogenesis of osteoporosis and the estrogen receptor
has been suggested as a possible candidate gene for regulation of bone mineral density …

Relationship of estrogen receptor genotypes to bone mineral density and to rates of bone loss in men

S Khosla, BL Riggs, EJ Atkinson… - The Journal of …, 2004 - academic.oup.com
Estrogen is now known to play an important role in bone metabolism in men. Thus, we
examined possible relationships between polymorphisms of the estrogen receptor (ER)-α …

Evidence of a linkage disequilibrium between polymorphisms in the human estrogen receptor α gene and their relationship to bone mass variation in postmenopausal …

L Becherini, L Gennari, L Masi… - Human molecular …, 2000 - academic.oup.com
Bone mineral density (BMD), the major determinant of osteoporotic fracture risk, has a strong
genetic component. The discovery that inactivation of estrogen receptor α (ER α) gene is …