Cerebrovascular dysfunction has been suggested as a physiomarker of Alzheimer's disease
(AD)-associated neuronal degeneration, but the underlying mechanisms are still debated …

Background This study was performed to explore the possible contributions of cerebral
hemodynamic changes to the cognitive impairment in patients with Alzheimer's disease …

The in vivo diagnosis of Alzheimer's disease (AD) may be facilitated by cerebro-spinal fluid
(CSF) biomarkers in combination with imaging and clinical assessments. By determining the …

Background. Recent studies have shown that cerebral vascularity may be impaired in
Alzheimer's disease. Cerebral vasomotor reactivity could be an important biomarker for this …

Cerebrovascular disease may contribute to the development and progression of Alzheimer's
disease (AD). This study investigated whether impairments in cerebral hemodynamics can …

ABSTRACT BACKGROUND AND PURPOSE A substantial overlap exists between declines
in cerebral vasoreactivity (CVR) and symptomatic Alzheimer's disease (AD). CVR can be …

Background Potential role of vascular dysfunction has been suggested in the pathogenesis
of Alzheimer's disease (AD). Previous cross-sectional studies have demonstrated relations …

Background: Increasing evidence shows early vascular dysregulation in the
pathophysiology of Alzheimer's disease (AD) in elderly population. Objective: We wondered …

Objective: To investigate variation in the characteristics of regional cerebral blood flow
(rCBF), brain activity, and intrinsic functional connectivity (FC) across the Alzheimer's …

ObjectiveOur recent single-photon emission computed tomography (SPECT) study of
patients with late-onset Alzheimer's disease (AD) revealed that regional cerebral blood flow …