Obesity and breast cancer: current insights on the role of fatty acids and lipid metabolism in promoting breast cancer growth and progression

C Blücher, SC Stadler - Frontiers in endocrinology, 2017 - frontiersin.org
Obesity and excess accumulation of adipose tissue are known risk factors for several types
of cancer, including breast cancer. With the incidence of obesity constantly rising worldwide …

Contribution of adipocytes in the tumor microenvironment to breast cancer metabolism

X Lyu, Q Zhang, HM Fares, Y Wang, Y Han, L Sun - Cancer Letters, 2022 - Elsevier
Breast cancer is considered the most common malignancy, with the profound ability to
perform a wide range of metabolic reprogramming. Within the breast cancer …

Updated clinical evidence on the role of adipokines and breast cancer: a review

GI Verras, L Tchabashvili, DD Chlorogiannis, F Mulita… - Cancers, 2023 - mdpi.com
Simple Summary Breast cancer is currently one of the most common types of cancer and the
number one cause of cancer-related deaths in women worldwide. Despite significant …

[HTML][HTML] Metabolic pathways in obesity-related breast cancer

KA Brown - Nature Reviews Endocrinology, 2021 - nature.com
This Review focuses on the mechanistic evidence for a link between obesity, dysregulated
cellular metabolism and breast cancer. Strong evidence now links obesity with the …

[HTML][HTML] Adipose tissue-to-breast cancer crosstalk: Comprehensive insights

Y Wu, X Li, Q Li, C Cheng, L Zheng - … et Biophysica Acta (BBA)-Reviews on …, 2022 - Elsevier
The review focuses on mechanistic evidence for the link between obesity and breast cancer.
According to the IARC study, there is sufficient evidence that obesity is closely related to a …

Adipose tissue as target organ in the treatment of hormone‐dependent breast cancer: new therapeutic perspectives

A Maccio, C Madeddu, G Mantovani - obesity reviews, 2009 - Wiley Online Library
Breast cancer is the female malignant neoplasia with the highest incidence in the
industrialized world. Despite many undeniable therapeutic successes obtained, breast …

Obese adipose tissue as a driver of breast cancer growth and development: update and emerging evidence

P Bhardwaj, KA Brown - Frontiers in Oncology, 2021 - frontiersin.org
Obesity is an established risk factor for breast cancer growth and progression. A number of
advances have been made in recent years revealing new insights into this link. Early events …

Unraveling the obesity and breast cancer links: a role for cancer-associated adipocytes?

L Bochet, G Escourrou, P Valet, C Muller - Adipose Tissue …, 2010 - karger.com
In addition to diabetes and cardiovascular diseases, epidemiological evidence
demonstrates that people who are obese or overweight are at increased risk of developing …

[HTML][HTML] Obesity, insulin resistance, adipocytokines and breast cancer: New biomarkers and attractive therapeutic targets

M Dalamaga - World journal of experimental medicine, 2013 - ncbi.nlm.nih.gov
Worldwide, breast cancer (BC) represents the most common type of non-skin human
malignancy and the second leading cause of cancer-related deaths amid women in Western …

Multifaceted breast cancer: the molecular connection with obesity

A Feola, S Ricci, S Kouidhi, A Rizzo… - Journal of Cellular …, 2017 - Wiley Online Library
Obesity is characterized by a disruption in energy balance regulation that results in an
excess accumulation of body fat. Its increasing prevalence poses a major public health …