[HTML][HTML] Prefrontal cortex predicts state switches during reversal learning

R Bartolo, BB Averbeck - Neuron, 2020 - cell.com
Reinforcement learning allows organisms to predict future outcomes and to update their
beliefs about value in the world. The dorsal-lateral prefrontal cortex (dlPFC) integrates …

Counterfactual choice and learning in a neural network centered on human lateral frontopolar cortex

ED Boorman, TE Behrens, MF Rushworth - PLoS biology, 2011 - journals.plos.org
Decision making and learning in a real-world context require organisms to track not only the
choices they make and the outcomes that follow but also other untaken, or counterfactual …

Prefrontal mechanisms combining rewards and beliefs in human decision-making

M Rouault, J Drugowitsch, E Koechlin - Nature Communications, 2019 - nature.com
In uncertain and changing environments, optimal decision-making requires integrating
reward expectations with probabilistic beliefs about reward contingencies. Little is known …

Volatility facilitates value updating in the prefrontal cortex

B Massi, CH Donahue, D Lee - Neuron, 2018 - cell.com
Adaptation of learning and decision-making might depend on the regulation of activity in the
prefrontal cortex. Here we examined how volatility of reward probabilities influences …

Metaplasticity as a neural substrate for adaptive learning and choice under uncertainty

S Farashahi, CH Donahue, P Khorsand, H Seo, D Lee… - Neuron, 2017 - cell.com
Value-based decision making often involves integration of reward outcomes over time, but
this becomes considerably more challenging if reward assignments on alternative options …

Dynamic routing of task-relevant signals for decision making in dorsolateral prefrontal cortex

CH Donahue, D Lee - Nature neuroscience, 2015 - nature.com
Neurons in the dorsolateral prefrontal cortex (DLPFC) encode a diverse array of sensory
and mnemonic signals, but little is known about how this information is dynamically routed …

Amygdala and ventral striatum make distinct contributions to reinforcement learning

VD Costa, O Dal Monte, DR Lucas, EA Murray… - Neuron, 2016 - cell.com
Reinforcement learning (RL) theories posit that dopaminergic signals are integrated within
the striatum to associate choices with outcomes. Often overlooked is that the amygdala also …

Predictive decision making driven by multiple time-linked reward representations in the anterior cingulate cortex

MK Wittmann, N Kolling, R Akaishi, BKH Chau… - Nature …, 2016 - nature.com
In many natural environments the value of a choice gradually gets better or worse as
circumstances change. Discerning such trends makes predicting future choice values …

Stable representations of decision variables for flexible behavior

BA Bari, CD Grossman, EE Lubin, AE Rajagopalan… - Neuron, 2019 - cell.com
Decisions occur in dynamic environments. In the framework of reinforcement learning, the
probability of performing an action is influenced by decision variables. Discrepancies …

Neural computations underlying inverse reinforcement learning in the human brain

S Collette, WM Pauli, P Bossaerts, J O'Doherty - Elife, 2017 - elifesciences.org
In inverse reinforcement learning an observer infers the reward distribution available for
actions in the environment solely through observing the actions implemented by another …