Autophagic flux disruption contributes to Ganoderma lucidum polysaccharide-induced apoptosis in human colorectal cancer cells via MAPK/ERK activation
H Pan, Y Wang, K Na, Y Wang, L Wang, Z Li… - Cell death & …, 2019 - nature.com
Targeting autophagy may serve as a promising strategy for cancer therapy. Ganoderma
lucidum polysaccharide (GLP) has been shown to exert promising anti-cancer effects …
lucidum polysaccharide (GLP) has been shown to exert promising anti-cancer effects …
Triterpenes From Ganoderma Lucidum Induce Autophagy in Colon Cancer Through the Inhibition of p38 Mitogen-Activated Kinase (p38 MAPK)
Medicinal mushroom Ganoderma lucidum is one of the most esteemed natural products that
have been used in the traditional Chinese medicine. In this article, we demonstrate that G …
have been used in the traditional Chinese medicine. In this article, we demonstrate that G …
Effect of Ganoderma applanatum polysaccharides on MAPK/ERK pathway affecting autophagy in breast cancer MCF-7 cells
X Hanyu, L Lanyue, D Miao, F Wentao… - International journal of …, 2020 - Elsevier
Fungal polysaccharides have become hotspots in the field of health foods due to their
antitumor activity in recent years. In this experiment, antitumor effect of the medicinal fungus …
antitumor activity in recent years. In this experiment, antitumor effect of the medicinal fungus …
[HTML][HTML] Polysaccharide from spore of Ganoderma lucidum ameliorates paclitaxel-induced intestinal barrier injury: Apoptosis inhibition by reversing microtubule …
D Li, L Gao, M Li, Y Luo, Y Xie, T Luo, L Su… - Biomedicine & …, 2020 - Elsevier
Side effects of chemotherapy are burning questions for physicians and patients involved in
cancers. Ganoderma lucidum is a widely consumed traditional Chinese medicine and edible …
cancers. Ganoderma lucidum is a widely consumed traditional Chinese medicine and edible …
Ganoderma atrum polysaccharide ameliorates intestinal mucosal dysfunction associated with autophagy in immunosuppressed mice
M Ying, B Zheng, Q Yu, K Hou, H Wang, M Zhao… - Food and Chemical …, 2020 - Elsevier
The aim of this study was to investigate the protective effect and underlying mechanisms of
Ganoderma atrum polysaccharide (PSG-1) on cyclophosphamide (Cy)-induced intestinal …
Ganoderma atrum polysaccharide (PSG-1) on cyclophosphamide (Cy)-induced intestinal …
Agrocybe cylindracea fucoglucogalactan induced lysosome-mediated apoptosis of colorectal cancer cell through H3K27ac-regulated cathepsin D
Z Wang, K Chen, K Zhang, K He, D Zhang, X Guo… - Carbohydrate …, 2023 - Elsevier
Inducing lysosomal dysfunction is emerging as a promising means for cancer therapy.
Agrocybe cylindracea fucoglucogalactan (ACP) is a bioactive ingredient with anti-tumor …
Agrocybe cylindracea fucoglucogalactan (ACP) is a bioactive ingredient with anti-tumor …
Inhibition of lysosome degradation on autophagosome formation and responses to GMI, an immunomodulatory protein from Ganoderma microsporum
BACKGROUND AND PURPOSE Autophagic cell death is considered a self‐destructive
process that results from large amounts of autophagic flux. In our previous study, GMI, a …
process that results from large amounts of autophagic flux. In our previous study, GMI, a …
Inhibition of migration and induction of apoptosis in LoVo human colon cancer cells by polysaccharides from Ganoderma lucidum
ZE Liang, YJ Yi, YT Guo, RC Wang… - Molecular …, 2015 - spandidos-publications.com
Ganoderma lucidum polysaccharides (GLPs), which were purified from the medicinal herb
G. lucidum followed by ethanol precipitation, protein depletion using the Sevage assay …
G. lucidum followed by ethanol precipitation, protein depletion using the Sevage assay …
Aloe gel glucomannan induced colon cancer cell death via mitochondrial damage-driven PINK1/Parkin mitophagy pathway
K Zhang, D Zhang, J Wang, Y Wang, J Hu, Y Zhou… - Carbohydrate …, 2022 - Elsevier
Mitophagy can selectively remove damaged mitochondria, which is critical in regulating
mitochondrial homeostasis in diseases, such as cancer. Herein, we found that Aloe gel …
mitochondrial homeostasis in diseases, such as cancer. Herein, we found that Aloe gel …
[HTML][HTML] Shikonin induces colorectal carcinoma cells apoptosis and autophagy by targeting galectin-1/JNK signaling axis
N Zhang, F Peng, Y Wang, L Yang, F Wu… - … Journal of Biological …, 2020 - ncbi.nlm.nih.gov
Colorectal carcinoma (CRC) is the third most common malignant tumor pathology
worldwide. Despite progress in surgical procedures and therapy options, CRC is still a …
worldwide. Despite progress in surgical procedures and therapy options, CRC is still a …