[HTML][HTML] Neuroimaging-based biomarkers for pain: state of the field and current directions

MM Van Der Miesen, MA Lindquist, TD Wager - Pain reports, 2019 - journals.lww.com
Chronic pain is an endemic problem involving both peripheral and brain pathophysiology.
Although biomarkers have revolutionized many areas of medicine, biomarkers for pain have …

The search for pain biomarkers in the human brain

A Mouraux, GD Iannetti - Brain, 2018 - academic.oup.com
Non-invasive functional brain imaging is used more than ever to investigate pain in health
and disease, with the prospect of finding new means to alleviate pain and improve patient …

[HTML][HTML] Neuroimaging-based pain biomarkers: definitions, clinical and research applications, and evaluation frameworks to achieve personalized pain medicine

S Mackey, HT Greely, KT Martucci - Pain reports, 2019 - journals.lww.com
One of the key ambitions of neuroimaging-based pain biomarker research is to augment
patient and clinician reporting of clinically relevant phenomena with neural measures for …

[HTML][HTML] Biomarkers for chronic pain and analgesia. Part 1: the need, reality, challenges, and solutions

D Borsook, L Becerra, R Hargreaves - Discovery medicine, 2011 - discoverymedicine.com
Chronic pain remains a significant clinical problem that has few effective therapies. Currently
the success rate for treating chronic pain with analgesics is around 30%. Both treatment and …

Neuroimaging enters the pain biomarker arena

I Tracey - Science translational medicine, 2021 - science.org
Neuroimaging enters the pain biomarker arena | Science Translational Medicine news careers
commentary Journals Science Science brought to you byGoogle Indexer Log in science …

[HTML][HTML] Composite pain biomarker signatures for objective assessment and effective treatment

I Tracey, CJ Woolf, NA Andrews - Neuron, 2019 - cell.com
Pain is a subjective sensory experience that can, mostly, be reported but cannot be directly
measured or quantified. Nevertheless, a suite of biomarkers related to mechanisms, neural …

[HTML][HTML] Biomarkers for chronic pain and analgesia. Part 2: how, where, and what to look for using functional imaging

D Borsook, L Becerra, R Hargreaves - Discovery medicine, 2011 - discoverymedicine.com
Rapid advances in brain imaging chronic pain patients have yielded exciting data sets that
could provide the basis for the development of chronic pain biomarkers that could increase …

[HTML][HTML] Objective pain assessment: a key for the management of chronic pain

X Xu, Y Huang - F1000Research, 2020 - ncbi.nlm.nih.gov
The individual and social burdens associated with chronic pain have been escalating
globally. Accurate pain measurement facilitates early diagnosis, disease progression …

[HTML][HTML] Discovery and validation of biomarkers to aid the development of safe and effective pain therapeutics: challenges and opportunities

KD Davis, N Aghaeepour, AH Ahn, MS Angst… - Nature Reviews …, 2020 - nature.com
Pain medication plays an important role in the treatment of acute and chronic pain
conditions, but some drugs, opioids in particular, have been overprescribed or prescribed …

Personalized treatment of neuropathic pain: Where are we now?

D Bouhassira, N Attal - European Journal of Pain, 2023 - Wiley Online Library
Background The treatment of neuropathic pain remains a major unmet need that the
development of personalized and refined treatment strategies may contribute to address …