Alternative splicing (AS) is a pervasive and vital mechanism involved in the progression of
cancer by expanding genomic encoding capacity and increasing protein complexity …

Background Alternative splicing (AS) is a transcriptional regulation mechanism, which can
expand the coding ability of genome and contribute to the occurrence and development of …

Accumulating evidence indicates an unexpected role of aberrant splicing in hepatocellular
carcinoma (HCC) that has been seriously neglected in previous studies. There is a need for …

Most genes are alternatively spliced and increasing number of evidences show that
alternative splicing (AS) is modified and related to tumor progression. Systematic profiles of …

Growing evidence showed that alternative splicing (AS) event is significantly related to tumor
occurrence and progress. This study was performed to make a systematic analysis of AS …

Alternative splicing (AS) is assumed to be a pivotal determinant for the generation of diverse
transcriptional variants in cancer. However, the comprehensive dysregulation of AS and the …

As the most common neoplasm in digestive system, hepatocellular carcinoma (HCC) is one
of the most important leading cause of cancer deaths worldwide. Its high-frequency …

Previous studies have demonstrated the role of abnormal alternative splicing (AS) in tumor
progression. This study examines the prognostic index (PI) of alternative splices (ASs) in …

Alternative splicing (AS) is a transcriptional regulation mechanism that participates in
multiple aspects of cancer. The present study aimed to identify differential AS events from …

Alternative splicing events (ASEs) play a role in cancer development and progression. We
investigated whether ASEs are prognostic for overall survival (OS) in hepatocellular …