Although genetic susceptibility explains the clustering of multiple sclerosis (MS) within
families and the sharp decline in risk with increasing genetic distance, it cannot fully explain …

Although genetic susceptibility explains the clustering of multiple sclerosis (MS) within
families and the sharp decline in risk with increasing genetic distance, it cannot fully explain …

Although genetic susceptibility explains the clustering of multiple sclerosis (MS) cases within
families, the changes in MS risk that occur with migration can be explained only by changes …

As discussed in Part I of this review, the geographic distribution of multiple sclerosis (MS)
and the change in risk among migrants provide compelling evidence for the existence of …

MS-pathogenesis involves both genetic-susceptibility and environmental determinants.
Three (or more) sequential environmental-factors are implicated. The first acts near birth, the …

Although strong genetic determinants of multiple sclerosis (MS) exist, the findings of
migration studies support a role for environmental factors in this disease. Through rigorous …

Hundreds of publications dealing with the prevalence of multiple sclerosis (MS) throughout
the world exist, but little data have been published from South America. Epidemiological …

Objectives–Multiple sclerosis (MS) likely results from an interaction between genetic and
exogenous factors. While genetics shapes the overall population MS susceptibility …

Although the cause of multiple sclerosis (MS) is unknown, epidemiologic studies support
both genetic and environmental components of susceptibility. Reports of clusters, small …

Multiple sclerosis (MS) is the most common disease of the central nervous system that
causes permanent disability in young adults. 1 Based on strong circumstantial evidence, MS …