The effect of short silica fibers (0.3 μm 3.2 μm) on macrophages

M Olejnik, M Breisch, V Sokolova, K Loza… - Science of The Total …, 2021 - Elsevier
Silica fibers with a dimension of 0.3 μm∙ 3.2 μm 2 nm were prepared by a modified Stöber
synthesis as model particles. The particles were characterized by scanning electron …

Subtoxic cell responses to silica particles with different size and shape

M Kersting, M Olejnik, N Rosenkranz, K Loza… - Scientific Reports, 2020 - nature.com
Health risks from particles are a priority challenge to health protection at work. Despite the
ubiquitous exposure to a wide range of particles and the many years of research in this field …

Evidence of size-dependent effect of silica micro-and nano-particles on basal and specialized monocyte functions

MC De Marzi, M Saraceno, R Mitarotonda… - Therapeutic …, 2017 - Taylor & Francis
Aim: To analyze the effect of silica particles on monocyte/macrophage functions. Materials &
methods: Silica micro-and nanoparticles were obtained by the Stöber method. Their effect …

In vitro effects on macrophages induced by noncytotoxic doses of silica particles possibly relevant to ambient exposure

M Balduzzi, M Diociaiuti, B De Berardis, S Paradisi… - Environmental …, 2004 - Elsevier
The RAW 246.7 macrophage cell line was exposed in vitro to aged crystalline silica particles
of respirable size for 24h at a range of doses starting from 15μg/2× 106 cells, which is a …

Effect of surface modification of silica nanoparticles on toxicity and cellular uptake by human peripheral blood lymphocytes in vitro

A Lankoff, M Arabski, A Wegierek-Ciuk… - …, 2013 - Taylor & Francis
Silica nanoparticles have an interesting potential in drug delivery, gene therapy and
molecular imaging due to the possibility of tailoring their surface reactivity that can be …

In vitro cytotoxicitiy of silica nanoparticles at high concentrations strongly depends on the metabolic activity type of the cell line

JS Chang, KLB Chang, DF Hwang… - Environmental science & …, 2007 - ACS Publications
Amorphous silica is increasingly used in diagnostic and biomedical research because of its
ease of production and relatively low cost. It is generally regarded as safe and has been …

Silica nanoconstruct cellular toleration threshold in vitro

HL Herd, A Malugin, H Ghandehari - Journal of controlled release, 2011 - Elsevier
The influence of geometry of silica nanomaterials on cellular uptake and toxicity on epithelial
and phagocytic cells was studied. Three types of amine-terminated silica nanomaterials …

Nano-sized silica particles: Cytotoxicity and cytokine responses in lung cell models involving differentiated THP-1 cells

LD Kadir - 2016 - duo.uio.no
Nanoparticles are available in a wide range of products, like pharmaceutical product and
cosmetics and in the last decade it has been an increasing use of silica nanoparticles …

In vitro evaluation of cytotoxic and inflammatory properties of silica nanoparticles of different sizes in murine RAW 264.7 macrophages

MVDZ Park, I Lynch, S Ramírez-García… - Journal of Nanoparticle …, 2011 - Springer
The biological response to four well-characterized amorphous silica nanoparticles was
investigated in RAW 264.7 macrophages in view of their potential application as drug …

Differences in gene expression and cytokine production by crystalline vs. amorphous silica in human lung epithelial cells

TN Perkins, A Shukla, PM Peeters… - Particle and fibre …, 2012 - Springer
Background Exposure to respirable crystalline silica particles, as opposed to amorphous
silica, is associated with lung inflammation, pulmonary fibrosis (silicosis), and potentially …