The mechanobiology theory of the development of medical device-related pressure ulcers revealed through a cell-scale computational modeling framework
Pressure ulcers are localized sites of tissue damage which form due to the continuous
exposure of skin and underlying soft tissues to sustained mechanical loading, by …
exposure of skin and underlying soft tissues to sustained mechanical loading, by …
Membrane permeability during pressure ulcer formation: A computational model of dynamic competition between cytoskeletal damage and repair
NS Jagannathan, L Tucker-Kellogg - Journal of biomechanics, 2016 - Elsevier
Pressure ulcers are debilitating wounds that arise frequently in people who have lost
mobility. Mechanical stress, oxidative stress and ischemia–reperfusion injury are potential …
mobility. Mechanical stress, oxidative stress and ischemia–reperfusion injury are potential …
Pressure ulcers and deep tissue injury: a bioengineering perspective
L Agam, A Gefen - Journal of wound care, 2007 - magonlinelibrary.com
Pressure ulcers are one of the most serious complications in paralysed and immobilised
patients, with severe consequences such as sepsis, osteomyelitis, renal failure and …
patients, with severe consequences such as sepsis, osteomyelitis, renal failure and …
Biomechanics of pressure ulcer in body tissues interacting with external forces during locomotion
Forces acting on the body via various external surfaces during locomotion are needed to
support the body under gravity, control posture, and overcome inertia. Examples include the …
support the body under gravity, control posture, and overcome inertia. Examples include the …
Linking microvascular collapse to tissue hypoxia in a multiscale model of pressure ulcer initiation
Pressure ulcers are devastating injuries that disproportionately affect the older adult
population. The initiating factor of pressure ulcers is local ischemia, or lack of perfusion at …
population. The initiating factor of pressure ulcers is local ischemia, or lack of perfusion at …
[图书][B] Bioengineering research of chronic wounds: a multidisciplinary study approach
A Gefen - 2009 - books.google.com
Pressure-related chronic wounds are an important health concern that affects millions of
patients and accumulates billions in annual costs. These wounds may occur when soft …
patients and accumulates billions in annual costs. These wounds may occur when soft …
A theoretical analysis of damage evolution in skeletal muscle tissue with reference to pressure ulcer development
RGM Breuls, CVC Bouten… - J. Biomech …, 2003 - asmedigitalcollection.asme.org
Soft tissues are sensitive to prolonged compressive loading, eventually leading to tissue
necrosis in the form of pressure ulcers 1. Pressure ulcers can occur in situations where …
necrosis in the form of pressure ulcers 1. Pressure ulcers can occur in situations where …
Bioengineering models of deep tissue injury
A Gefen - Advances in skin & wound care, 2008 - journals.lww.com
For patients permanently confined to a wheelchair or a bed, pressure ulcers are a major
health risk. Pressure ulcers typically appear in soft tissues enveloping bony prominences …
health risk. Pressure ulcers typically appear in soft tissues enveloping bony prominences …
Bioengineering considerations in the prevention of medical device-related pressure ulcers
DL Bader, PR Worsley, A Gefen - Clinical Biomechanics, 2019 - Elsevier
Background In recent years, it has become increasingly apparent that medical device-
related pressure ulcers represent a significant burden to both patients and healthcare …
related pressure ulcers represent a significant burden to both patients and healthcare …
Cytoskeleton and plasma-membrane damage resulting from exposure to sustained deformations: a review of the mechanobiology of chronic wounds
The purpose of this review paper is to summarize the current knowledge on cell-scale
mechanically-inflicted deformation-damage, which is at the frontier of cell mechanobiology …
mechanically-inflicted deformation-damage, which is at the frontier of cell mechanobiology …
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