[HTML][HTML] Oligofructose improves small intestinal lipid-sensing mechanisms via alterations to the small intestinal microbiota

SN Weninger, C Herman, RK Meyer, ET Beauchemin… - Microbiome, 2023 - Springer
Background Upper small intestinal dietary lipids activate a gut-brain axis regulating energy
homeostasis. The prebiotic, oligofructose (OFS) improves body weight and adiposity during …

Alleviation of high fat diet‐induced obesity by oligofructose in gnotobiotic mice is independent of presence of Bifidobacterium longum

A Woting, N Pfeiffer, L Hanske, G Loh… - Molecular nutrition & …, 2015 - Wiley Online Library
Scope Diet‐induced obesity is associated with changes in the gut microbiota and low‐grade
inflammation. Oligofructose was reported to ameliorate high fat diet‐induced metabolic …

[HTML][HTML] Combined soluble fiber-mediated intestinal microbiota improve insulin sensitivity of obese mice

C Xu, J Liu, J Gao, X Wu, C Cui, H Wei, R Zheng… - Nutrients, 2020 - mdpi.com
Dietary fiber, an important regulator of intestinal microbiota, is a promising tool for preventing
obesity and related metabolic disorders. However, the functional links between dietary fiber …

[HTML][HTML] 2′-fucosyllactose supplementation improves gut-brain signaling and diet-induced obese phenotype and changes the gut microbiota in high fat-fed mice

S Lee, M Goodson, W Vang, K Kalanetra, D Barile… - Nutrients, 2020 - mdpi.com
Obesity is characterized by fat accumulation, chronic inflammation and impaired satiety
signaling, which may be due in part to gut microbial dysbiosis. Manipulations of the gut …

Prebiotic oligofructose protects against high-fat diet-induced obesity by changing the gut microbiota, intestinal mucus production, glycosylation and secretion

P Paone, F Suriano, C Jian, K Korpela… - Gut …, 2022 - Taylor & Francis
Obesity is a major risk factor for the development of type 2 diabetes and cardiovascular
diseases, and gut microbiota plays a key role in influencing the host energy homeostasis …

Different dietary fibers unequally remodel gut microbiota and charge up anti-obesity effects

JJ Wen, MZ Li, JL Hu, J Wang, ZQ Wang, CH Chen… - Food …, 2023 - Elsevier
Supplementation of certain bioactive dietary fibers could alleviate obesity induced by a high-
fat diet, whereas whether the responses of different polysaccharides are consistent remains …

[HTML][HTML] Microbiota-generated metabolites promote metabolic benefits via gut-brain neural circuits

F De Vadder, P Kovatcheva-Datchary, D Goncalves… - Cell, 2014 - cell.com
Soluble dietary fibers promote metabolic benefits on body weight and glucose control, but
underlying mechanisms are poorly understood. Recent evidence indicates that intestinal …

Interactive effects of oligofructose and obesity predisposition on gut hormones and microbiota in diet‐induced obese rats

NL Cluny, LK Eller, CM Keenan, RA Reimer… - …, 2015 - Wiley Online Library
Objective Oligofructose (OFS) is a prebiotic that reduces energy intake and fat mass via
changes in gut satiety hormones and microbiota. The effects of OFS may vary depending on …

Fish oil supplementation to a high-fat diet improves both intestinal health and the systemic obese phenotype

JM Monk, DM Liddle, AL Hutchinson, W Wu… - The Journal of nutritional …, 2019 - Elsevier
Impaired intestinal health characterized by a dysbiotic microbial community and a
dysfunctional epithelial barrier contributes to host inflammation and metabolic dysfunction in …

[HTML][HTML] Long-term high-fructose high-fat diet feeding elicits insulin resistance, exacerbates dyslipidemia and induces gut microbiota dysbiosis in WHHL rabbits

M Moughaizel, E Dagher, A Jablaoui, C Thorin… - Plos one, 2022 - journals.plos.org
The metabolic syndrome (MetS) has become a global public health burden due to its link to
cardiovascular disease and diabetes mellitus. The present study was designed to …