Clinical predictors of therapeutic response to antipsychotics in schizophrenia

M Carbon, CU Correll - Dialogues in clinical neuroscience, 2014 - Taylor & Francis
The search for clinical outcome predictors for schizophrenia is as old as the field of
psychiatry. However, despite a wealth of large, longitudinal studies into prognostic factors …

Pharmacologic treatment of schizophrenia

JM Kane, CU Correll - Dialogues in clinical neuroscience, 2010 - Taylor & Francis
Despite pharmacologic advances, the treatment of schizophrenia remains a challenge, and
suboptimal outcomes are still all too frequent. Although treatment goals of response …

Predictors of long-term outcome in schizophrenia

R Emsley, B Chiliza, R Schoeman - Current Opinion in Psychiatry, 2008 - journals.lww.com
Predictors of long-term outcome in schizophrenia : Current Opinion in Psychiatry Predictors of
long-term outcome in schizophrenia : Current Opinion in Psychiatry Log in or Register Subscribe …

Review Do atypical antipsychotic medications favorably alter the long-term course of schizophrenia?

JR DeQuardo, R Tandon - Journal of psychiatric research, 1998 - Elsevier
Schizophrenia is characterized by the greatest degree of clinical deterioration in the first
decade following onset of psychosis; in fact, deterioration begins even prior to the onset of …

Initial severity of schizophrenia and efficacy of antipsychotics: participant-level meta-analysis of 6 placebo-controlled studies

TA Furukawa, SZ Levine, S Tanaka, Y Goldberg… - JAMA …, 2015 - jamanetwork.com
Importance Antipsychotic drugs constitute the mainstay in the treatment of schizophrenia,
and their efficacy is well established in hundreds of randomized clinical trials. However, it is …

Psychobiologic correlates of treatment response in schizophrenia

JA Lieberman, JM Alvir, A Koreen, S Geisler… - …, 1996 - nature.com
In studies conducted on largely treatment naive patients in their first episode of psychosis,
we have found that treatment outcome is quite good and that most patients recover or at …

The long-term effects of antipsychotic medication on clinical course in schizophrenia

DC Goff, P Falkai, WW Fleischhacker… - American Journal of …, 2017 - Am Psychiatric Assoc
Concerns have been raised that treatment with antipsychotic medication might adversely
affect long-term outcomes for people with schizophrenia. The evidence cited for these …

Predicting drug efficacy for cognitive deficits in schizophrenia

JJ Hagan, DNC Jones - Schizophrenia Bulletin, 2005 - academic.oup.com
The purpose of this article is to discuss the prediction of cognitive enhancement in
schizophrenia from preclinical data. Despite increasing focus on the significance of cognitive …

Progress in defining optimal treatment outcome in schizophrenia

G Remington, G Foussias, O Agid - CNS drugs, 2010 - Springer
Historically, schizophrenia has been associated with early-onset, persistent symptoms, and
progressive decline accompanied by poor functional recovery. The advent of effective drugs …

Past and present progress in the pharmacologic treatment of schizophrenia

JM Kane, CU Correll - The Journal of clinical psychiatry, 2010 - psychiatrist.com
Despite treatment advances over the past decades, schizophrenia remains one of the most
severe psychiatric disorders that is associated with a chronic relapsing course and marked …