Stem cells respond to nanoscale surface features, with changes in cell growth and
differentiation mediated by alterations in cell adhesion. The interaction of nanotopographical …

Stem cells are increasingly studied because of their potential to underpin a range of novel
therapies, including regenerative strategies, cell type-specific therapy and tissue repair …

Adult stem cell research has been advanced in recent years because of the cells' attractive
abilities of self-renewal and differentiation. Topography of materials is one of the key …

Out of their niche environment, adult stem cells, such as mesenchymal stem cells (MSCs),
spontaneously differentiate. This makes both studying these important regenerative cells …

The differentiation of stem cells can be modulated by physical factors such as the micro-and
nano-topography of the extracellular matrix. One important goal in stem cell research is to …

Stem cells possess unique abilities as they can renew themselves for extended periods of
time and have the capacity to differentiate into a variety of lineages. They hold promise for …

Stem cells are unspecialized cells that can self renew indefinitely and differentiate into
several somatic cells given the correct environmental cues. In the stem cell niche, stem cell …

Nanotopography presents an effective physical approach for biomaterial cell manipulation
mediated through material-extracellular matrix interactions. The extracellular matrix that …

Influencing cell behavior from proliferation to differentiation using substrate or implant
topography is an attractive strategy for regenerative medicine applications. Substrate …

The interplay of biophysical and biochemical cues in the extracellular microenvironment
regulate and control the cell fate of stem cells. Understanding the interaction between stem …