A novel DNA damage repair gene-related prognostic model for evaluating the prognosis and tumor microenvironment infiltration of esophageal squamous cell …
D Guo, X Zhang, X Du, W Yao, W Shen, S Zhu - BMC Medical Genomics, 2023 - Springer
Background This study aimed to investigate the potential prognostic value of DNA damage
repair genes (DDRGs) in esophageal squamous cell carcinoma (ESCC) and their …
repair genes (DDRGs) in esophageal squamous cell carcinoma (ESCC) and their …
[HTML][HTML] Identification of a prognostic DNA repair gene signature in esophageal cancer
H Du, X Wang, S Xie, A Tartarone… - Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Background DNA repair plays a crucial role in the development and progression of different
types of cancers. Nevertheless, little is known about the role of DNA repair-related genes …
types of cancers. Nevertheless, little is known about the role of DNA repair-related genes …
Clinical prognostication and immunotherapy response prediction in esophageal squamous cell carcinoma using the DNA damage repair‐associated signature
P Zhang, B Wen, J Gong, Z Liu, M Zhang… - Environmental …, 2024 - Wiley Online Library
Background The relationship between DNA damage repair (DDR) and cancer is intricately
intertwined; however, its specific role in esophageal squamous cell carcinoma (ESCC) …
intertwined; however, its specific role in esophageal squamous cell carcinoma (ESCC) …
DNA damage repair profiling of esophageal squamous cell carcinoma uncovers clinically relevant molecular subtypes with distinct prognoses and therapeutic …
N Zhao, Z Zhang, Q Wang, L Li, Z Wei, H Chen… - …, 2023 - thelancet.com
Background DNA damage repair (DDR) is a critical process that maintains genomic integrity
and plays essential roles at both the cellular and organismic levels. Here, we aimed to …
and plays essential roles at both the cellular and organismic levels. Here, we aimed to …
Novel DNA damage repair signature for immunotherapy and a proposed molecular subtyping scheme in gastric cancer
X Li, C Wang, H Dong, J Chen, S Chen, M Li, H Chen… - 2024 - researchsquare.com
The DNA damage repair (DDR) mechanisms is closely related to the occurrence and
progression of cancer cells. The diversity and complexity of DNA repair mechanisms also …
progression of cancer cells. The diversity and complexity of DNA repair mechanisms also …
A DNA damage repair associated signature for HNSCC
Z Ma, W Liao, S Yang, Y Xu, G Chen, L Song, X Zhang - 2023 - researchsquare.com
Background: DNA damage repair (DDR) genes play a vital role in tumorigenesis and the
tumor microenvironment. However, the specific role of DDR genes in head and neck …
tumor microenvironment. However, the specific role of DDR genes in head and neck …
The effects of altered DNA damage repair genes on mutational processes and immune cell infiltration in esophageal squamous cell carcinoma
Background Defects in DNA damage repair (DDR) pathways lead to genomic instability and
oncogenesis. DDR deficiency is prevalent in esophageal squamous cell carcinoma (ESCC) …
oncogenesis. DDR deficiency is prevalent in esophageal squamous cell carcinoma (ESCC) …
Identification of DNA-repair-related five-gene signature to predict prognosis in patients with esophageal cancer
L Wang, X Li, L Zhao, L Jiang, X Song, A Qi… - Pathology and …, 2021 - por-journal.com
Esophageal cancer (ESCA) is a leading cause of cancer-related mortality, with poor
prognosis worldwide. DNA damage repair is one of the hallmarks of cancer. Loss of …
prognosis worldwide. DNA damage repair is one of the hallmarks of cancer. Loss of …
[PDF][PDF] Development of a prognostic signature for esophageal cancer based on a novel 7-DNA damage repair genes signature
J Zhan, W Wang, Y Tang, N Zhou, D Jiang - Biocell, 2022 - cdn.techscience.cn
Esophageal cancer (EC) was an aggressive malignant neoplasm characterized by high
morbidity and poor prognosis. Identifying the changes in DNA damage repair genes helps to …
morbidity and poor prognosis. Identifying the changes in DNA damage repair genes helps to …
Deleterious alterations of DNA damage response and repair genes and clinical benefit to anti-PD-1 therapy in esophageal squamous cell carcinoma
Background Although DNA damage response and repair (DDR) gene alteration has been
demonstrated as a biomarker for anti-PD-1 therapy in several cancer types, its role in …
demonstrated as a biomarker for anti-PD-1 therapy in several cancer types, its role in …
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