Rivaroxaban and aspirin in peripheral artery disease lower extremity revascularization: impact of concomitant clopidogrel on efficacy and safety

WR Hiatt, MP Bonaca, MR Patel, MR Nehler… - Circulation, 2020 - Am Heart Assoc
Background: The VOYAGER PAD trial (Vascular Outcomes Study of ASA Along With
Rivaroxaban in Endovascular or Surgical Limb Revascularization for Peripheral Artery …

Effect of rivaroxaban and aspirin in patients with peripheral artery disease undergoing surgical revascularization: insights from the VOYAGER PAD trial

ES Debus, MR Nehler, N Govsyeyev, RM Bauersachs… - Circulation, 2021 - Am Heart Assoc
Background: Patients with peripheral artery disease requiring lower extremity
revascularization (LER) are at high risk of adverse limb and cardiovascular events. The …

Reduction in acute limb ischemia with rivaroxaban versus placebo in peripheral artery disease after lower extremity revascularization: insights from VOYAGER PAD

CN Hess, ES Debus, MR Nehler, SS Anand, MR Patel… - Circulation, 2021 - Am Heart Assoc
Background: Patients with peripheral artery disease (PAD) are at heightened risk of acute
limb ischemia (ALI), a thrombotic event associated with amputation, disability, and mortality …

Total ischemic event reduction with rivaroxaban after peripheral arterial revascularization in the VOYAGER PAD trial

RM Bauersachs, M Szarek, M Brodmann, I Gudz… - Journal of the American …, 2021 - jacc.org
Background Patients with peripheral artery disease (PAD) undergoing lower extremity
revascularization (LER) are at high risk of major adverse limb and cardiovascular events …

Rationale and design for the Vascular Outcomes study of ASA along with rivaroxaban in endovascular or surgical limb revascularization for peripheral artery disease …

WH Capell, MP Bonaca, MR Nehler, E Chen… - American heart …, 2018 - Elsevier
Background Patients with peripheral artery disease (PAD) undergoing a lower-extremity
revascularization are at heightened risk for ischemic cardiac and limb events. Although …

Rivaroxaban in peripheral artery disease after revascularization

MP Bonaca, RM Bauersachs, SS Anand… - … England Journal of …, 2020 - Mass Medical Soc
Background Patients with peripheral artery disease who have undergone lower-extremity
revascularization are at high risk for major adverse limb and cardiovascular events. The …

Rivaroxaban and aspirin in patients with symptomatic lower extremity peripheral artery disease: a subanalysis of the COMPASS randomized clinical trial

E Kaplovitch, JW Eikelboom, L Dyal, V Aboyans… - JAMA …, 2021 - jamanetwork.com
Importance Patients with symptomatic lower extremity peripheral artery disease (LE-PAD)
experience an increased risk of major vascular events. There is limited information on what …

Edoxaban plus aspirin vs dual antiplatelet therapy in endovascular treatment of patients with peripheral artery disease: results of the ePAD trial

F Moll, I Baumgartner, M Jaff… - Journal of …, 2018 - journals.sagepub.com
Purpose: To report a randomized study that investigated the safety (risk of major bleeds) and
potential efficacy of edoxaban, an oral anticoagulant that targets the major components of …

Ticagrelor compared with clopidogrel in patients with prior lower extremity revascularization for peripheral artery disease

WS Jones, I Baumgartner, WR Hiatt, G Heizer… - Circulation, 2017 - Am Heart Assoc
Background: In patients with symptomatic peripheral artery disease with a history of limb
revascularization, the optimal antithrombotic regimen for long-term management is …

A structured review of antithrombotic therapy in peripheral artery disease with a focus on revascularization: a TASC (InterSociety Consensus for the Management of …

CN Hess, L Norgren, GM Ansel, WH Capell… - Circulation, 2017 - Am Heart Assoc
Peripheral artery disease affects> 200 million people worldwide and is associated with
significant limb and cardiovascular morbidity and mortality. Limb revascularization is …