Hydroxychavicol, a betel leaf component, inhibits prostate cancer through ROS-driven DNA damage and apoptosis
SR Gundala, C Yang, R Mukkavilli, R Paranjpe… - Toxicology and applied …, 2014 - Elsevier
Dietary phytochemicals are excellent ROS-modulating agents and have been shown to
effectively enhance ROS levels beyond toxic threshold in cancer cells to ensure their …
effectively enhance ROS levels beyond toxic threshold in cancer cells to ensure their …
Piper Betel Leaf: A Reservoir of Potential Xenohormetic Nutraceuticals with Cancer-Fighting Properties
SR Gundala, R Aneja - Cancer Prevention Research, 2014 - AACR
Plants contain a much greater diversity of bioactive compounds than any man-made
chemical library. Heart-shaped Piper betel leaves are magnificent reservoirs of phenolic …
chemical library. Heart-shaped Piper betel leaves are magnificent reservoirs of phenolic …
[HTML][HTML] Isobavachalcone Induces ROS-Mediated Apoptosis via Targeting Thioredoxin Reductase 1 in Human Prostate Cancer PC-3 Cells
K Li, Q Zheng, X Chen, Y Wang, D Wang… - Oxidative medicine and …, 2018 - hindawi.com
Prostate carcinoma causes a great number of deaths every year; therefore, there is an
urgent need to find new drug candidates to treat advanced prostate cancer …
urgent need to find new drug candidates to treat advanced prostate cancer …
Molecular insights on chemopreventive and anticancer potential of carvacrol: Implications from solid carcinomas
Globally, cancer is one of the deadliest diseases, estimated to cause 9.9 million deaths in
2020. Conventional cancer treatments commonly involve mono‐chemotherapy or a …
2020. Conventional cancer treatments commonly involve mono‐chemotherapy or a …
Carvacrol Induces Reactive Oxygen Species (ROS)-mediated Apoptosis Along with Cell Cycle Arrest at G0/G1 in Human Prostate Cancer Cells
Carvacrol, a major monoterpenoid phenol from Origanum and Thymus species, has been
shown to exhibit antiproliferative and anticancer properties in a few recent studies …
shown to exhibit antiproliferative and anticancer properties in a few recent studies …
[HTML][HTML] Corosolic acid, a natural triterpenoid, induces ER stress-dependent apoptosis in human castration resistant prostate cancer cells via activation of IRE-1/JNK …
B Ma, H Zhang, Y Wang, A Zhao, Z Zhu, X Bao… - Journal of Experimental …, 2018 - Springer
Background The development of potent non-toxic chemotherapeutic drugs against
castration resistant prostate cancer (CRPC) remains a major challenge. Corosolic acid (CA) …
castration resistant prostate cancer (CRPC) remains a major challenge. Corosolic acid (CA) …
Hydroxychavicol from Piper betle induces apoptosis, cell cycle arrest, and inhibits epithelial-mesenchymal transition in pancreatic cancer cells
AG Majumdar, M Subramanian - Biochemical pharmacology, 2019 - Elsevier
Pancreatic cancer is a major cause of cancer-related mortality around the world. Currently,
options for diagnosis and treatment are extremely limited, which culminates in a very high …
options for diagnosis and treatment are extremely limited, which culminates in a very high …
Natural diterpenoid eriocalyxin B covalently modifies glutathione and selectively inhibits thioredoxin reductase inducing potent oxidative stress-mediated apoptosis in …
D Duan, Y Wang, X Jin, M Li, L Wang, Y Yan… - Free Radical Biology …, 2021 - Elsevier
Increasing evidence suggests the significant contribution of high levels of thioredoxin
reductase (TrxR) in various stages of tumorigenesis and resistance to tumor chemotherapy …
reductase (TrxR) in various stages of tumorigenesis and resistance to tumor chemotherapy …
[HTML][HTML] Cranberry proanthocyanidins inhibit esophageal adenocarcinoma in vitro and in vivo through pleiotropic cell death induction and PI3K/AKT/mTOR inactivation
LA Kresty, KM Weh, B Zeyzus-Johns, LN Perez… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Cranberries are rich in bioactive constituents known to improve urinary tract health and more
recent evidence supports cranberries possess cancer inhibitory properties. However …
recent evidence supports cranberries possess cancer inhibitory properties. However …
Berberine-induced apoptosis in human prostate cancer cells is initiated by reactive oxygen species generation
SM Meeran, S Katiyar, SK Katiyar - Toxicology and applied pharmacology, 2008 - Elsevier
Phytochemicals show promise as potential chemopreventive or chemotherapeutic agents
against various cancers. Here we report the chemotherapeutic effects of berberine, a …
against various cancers. Here we report the chemotherapeutic effects of berberine, a …