Whether melanogenesis occurs in adult eyes is still a matter of controversy. It has been
widely held that the pigment epithelial cells are fully melanized at birth, and that the uveal …

The melanocytes in the mammalian eye have been thought to produce melanin only during
fetal development and in the very young individual. The recent discovery that latanoprost, a …

Electron‐microscopic study of the size of the melanosomes, the mean percentage of
melanosomal profile area (MPMA) of the cells, and the duration of melanogenesis in the …

This paper is a review of what is known about the turnover of melanin in iris, choroid, and
retinal pigment epithelium (RPE) of the adult vertebrate eye. Differences in size and …

The tyrosinase activity in melanin‐forming tissues was investigated in a series of rats (6 days
to 1 year old), one cat 30 days old, and one 4 month old human fetus. The technique used …

PURPOSE: To study melanogenesis by cultured human uveal melanocytes, and the
relationship between melanin production by uveal melanocytes in vitro with the degree of …

Background: Ultraviolet radiation is thought to play a causative role in various ocular
diseases such as macular degeneration, cataract, and possibly melanomas. Since most of …

The purpose of this study was to investigate factors regulating melanogenesis in cultured
human uveal melanocytes. The effects of various substances on the melanin content …

This paper deals with our findings on the quantities of melanin in the tissues from blue and
brown eyes. The amount of melanin in the iris, ciliary body and retinal pigment epithelium …

Investigations were carried out to determine whether the melanin present in the blue and
brown eyes were eumelanin, the melanin present in black hair and dark skin, or …