Epidermal stem cells in wound healing and their clinical applications

R Yang, F Liu, J Wang, X Chen, J Xie… - Stem cell research & …, 2019 - Springer
The skin has important barrier, sensory, and immune functions, contributing to the health
and integrity of the organism. Extensive skin injuries that threaten the entire organism …

Epidermal stem cells in skin wound healing

Y Li, J Zhang, J Yue, X Gou, X Wu - Advances in wound care, 2017 - liebertpub.com
Significance: Skin serves as a protective barrier for mammals. Epidermal stem cells are
responsible for maintaining skin homeostasis. When cutaneous injuries occur, skin …

Epidermal stem cells in wound healing and regeneration

R Yang, J Wang, X Chen, Y Shi, J Xie - Stem cells international, 2020 - Wiley Online Library
Skin stem cells distributed in the basal layer of the epidermis and hair follicles are important
cell sources for skin development, metabolism, and injury repair. At present, great progress …

Proinflammatory cytokines regulate epidermal stem cells in wound epithelialization

T Xiao, Z Yan, S Xiao, Y Xia - Stem cell research & therapy, 2020 - Springer
The skin, which serves as the first barrier of the human body, is particularly susceptible to
exogenous injuries. Skin wounds, including acute burns and chronic non-healing ulcers, are …

Stem cells in skin regeneration, wound healing, and their clinical applications

N Ojeh, I Pastar, M Tomic-Canic… - International journal of …, 2015 - mdpi.com
The skin is the largest organ of the body and has an array of functions. Skin compartments,
epidermis, and hair follicles house stem cells that are indispensable for skin homeostasis …

Stem cells and their applications in skin-cell therapy

C Shi, Y Zhu, Y Su, T Cheng - TRENDS in Biotechnology, 2006 - cell.com
Skin stem cell biology is a rapidly advancing field in the life sciences. There is increasing
evidence that skin represents a larger reservoir for adult stem cells (including mesenchymal …

Skin and its regenerative powers: an alliance between stem cells and their niche

KAU Gonzales, E Fuchs - Developmental cell, 2017 - cell.com
Tissues have a natural capacity to replace dying cells and to heal wounds. This ability
resides in resident stem cells, which self-renew, preserve, and repair their tissue during …

A beginner's introduction to skin stem cells and wound healing

D Díaz-García, A Filipová, I Garza-Veloz… - International journal of …, 2021 - mdpi.com
The primary function of the skin is that of a physical barrier against the environment and
diverse pathogens; therefore, its integrity is essential for survival. Skin regeneration depends …

Epidermal stem cells: the cradle of epidermal determination, differentiation and wound healing

MI Morasso, M Tomic‐Canic - Biology of the Cell, 2005 - Wiley Online Library
The field of epidermal stem cells has dramatically advanced in the last decade, leading to a
better understanding of the molecular factors, signalling pathways and cellular events that …

Skin tissue engineering: wound healing based on stem-cell-based therapeutic strategies

A Nourian Dehkordi, F Mirahmadi Babaheydari… - Stem cell research & …, 2019 - Springer
Normal wound healing is a dynamic and complex multiple phase process involving
coordinated interactions between growth factors, cytokines, chemokines, and various cells …