Microfluidics for producing poly (lactic-co-glycolic acid)-based pharmaceutical nanoparticles
X Li, X Jiang - Advanced drug delivery reviews, 2018 - Elsevier
Microfluidic chips allow the rapid production of a library of nanoparticles (NPs) with distinct
properties by changing the precursors and the flow rates, significantly decreasing the time …
properties by changing the precursors and the flow rates, significantly decreasing the time …
[HTML][HTML] Translating the fabrication of protein-loaded poly (lactic-co-glycolic acid) nanoparticles from bench to scale-independent production using microfluidics
CB Roces, D Christensen, Y Perrie - Drug delivery and translational …, 2020 - Springer
In the formulation of nanoparticles, poly (lactic-co-glycolic acid)(PLGA) is commonly
employed due to its Food and Drug Administration and European Medicines Agency …
employed due to its Food and Drug Administration and European Medicines Agency …
[HTML][HTML] Microfluidic assisted synthesis of PLGA drug delivery systems
S Rezvantalab, MK Moraveji - RSC advances, 2019 - pubs.rsc.org
Poly (lactic-co-glycolic acid)(PLGA) is a biocompatible and biodegradable polymer that
recently attracted attention for use as part of drug delivery systems (DDS). In this context …
recently attracted attention for use as part of drug delivery systems (DDS). In this context …
[HTML][HTML] Microfluidics-assisted size tuning and biological evaluation of PLGA particles
MC Operti, Y Dölen, J Keulen, EAW van Dinther… - Pharmaceutics, 2019 - mdpi.com
Polymeric particles made up of biodegradable and biocompatible polymers such as poly
(lactic-co-glycolic acid)(PLGA) are promising tools for several biomedical applications …
(lactic-co-glycolic acid)(PLGA) are promising tools for several biomedical applications …
[HTML][HTML] Fabrication of PLGA nanoparticles with a fluidic nanoprecipitation system
H Xie, JW Smith - Journal of nanobiotechnology, 2010 - Springer
Particle size is a key feature in determining performance of nanoparticles as drug carriers
because it influences circulating half-life, cellular uptake and biodistribution. Because the …
because it influences circulating half-life, cellular uptake and biodistribution. Because the …
Recent Trends in Preparation of Poly(lactide‐co‐glycolide) Nanoparticles by Mixing Polymeric Organic Solution with Antisolvent
E Sah, H Sah - Journal of Nanomaterials, 2015 - Wiley Online Library
In recent years, there have been a plethora of nanoengineering approaches for the
development of poly (lactide‐co‐glycolide)(PLGA) nanoparticulate carrier systems …
development of poly (lactide‐co‐glycolide)(PLGA) nanoparticulate carrier systems …
[HTML][HTML] PLGA-based nanomedicines manufacturing: Technologies overview and challenges in industrial scale-up
MC Operti, A Bernhardt, S Grimm, A Engel… - International Journal of …, 2021 - Elsevier
Nanomedicines based on poly (lactic-co-glycolic acid)(PLGA) carriers offer tremendous
opportunities for biomedical research. Although several PLGA-based systems have already …
opportunities for biomedical research. Although several PLGA-based systems have already …
[HTML][HTML] Comparison of bulk and microfluidics methods for the formulation of poly-lactic-co-glycolic acid (PLGA) nanoparticles modified with cell-penetrating peptides …
S Streck, H Neumann, HM Nielsen, T Rades… - International journal of …, 2019 - Elsevier
The efficient and reproducible production of nanoparticles using bulk nanoprecipitation
methods is still challenging because of low batch to batch reproducibility. Here, we optimize …
methods is still challenging because of low batch to batch reproducibility. Here, we optimize …
The use of an efficient microfluidic mixing system for generating stabilized polymeric nanoparticles for controlled drug release
Y Morikawa, T Tagami, A Hoshikawa… - Biological and …, 2018 - jstage.jst.go.jp
Microfluidics is a promising system for efficiently optimizing the experimental conditions for
preparing nanomedicines, such as self-assembled nanoparticles. Poly (lactic-co-glycolic …
preparing nanomedicines, such as self-assembled nanoparticles. Poly (lactic-co-glycolic …
Engineered PLGA nanoparticles: an emerging delivery tool in cancer therapeutics
Nanocarriers formulated with the US Food and Drug Administration-approved biocompatible
and biodegradable polymer poly (lactic-co-glycolic acid)(PLGA) are being widely explored …
and biodegradable polymer poly (lactic-co-glycolic acid)(PLGA) are being widely explored …