[HTML][HTML] FABP1 and FABP2 as markers of diabetic nephropathy

IT Tsai, CC Wu, WC Hung, TL Lee… - … journal of medical …, 2020 - ncbi.nlm.nih.gov
Background: Diabetes mellitus is the leading cause of diabetic nephropathy and a major
public health issue worldwide. Approximately 20-30% of patients with type 2 diabetes …

Plasma fatty acid-binding protein 4 increases with renal dysfunction in type 2 diabetic patients without microalbuminuria

A Cabre, I Lazaro, J Girona, JM Manzanares… - Clinical …, 2008 - academic.oup.com
Background: Fatty acid–binding protein 4 (FABP4) has been linked to metabolic syndrome
development, diabetes, and arteriosclerosis, but the role of FABP4 in target organ damage …

[HTML][HTML] Urinary excretion of fatty acid-binding protein 4 is associated with albuminuria and renal dysfunction

Y Okazaki, M Furuhashi, M Tanaka, T Mita, T Fuseya… - PLoS …, 2014 - journals.plos.org
Background Fatty acid-binding protein 4 (FABP4/A-FABP/aP2) is expressed in not only
adipocytes and macrophages but also peritubular capillaries in the normal kidney. We …

Ectopic expression of fatty acid-binding protein 4 in the glomerulus is associated with proteinuria and renal dysfunction

M Tanaka, M Furuhashi, Y Okazaki, T Mita… - Nephron Clinical …, 2015 - karger.com
Abstract Background/Aims: Fatty acid-binding proteins (FABPs) are a family of intracellular
lipid chaperones. Among FABPs, FABP1 (liver FABP) is expressed in proximal tubular …

[HTML][HTML] Serum fatty acid-binding protein 4 is a predictor of cardiovascular events in end-stage renal disease

M Furuhashi, S Ishimura, H Ota, M Hayashi, T Nishitani… - Plos one, 2011 - journals.plos.org
Background Fatty acid-binding protein 4 (FABP4/A-FABP/aP2), a lipid chaperone, is
expressed in both adipocytes and macrophages. Recent studies have shown that FABP4 is …

Fatty acid-binding protein 4 is associated with endothelial dysfunction in patients with type 2 diabetes

G Aragonès, R Ferré, I Lázaro, A Cabré, N Plana… - Atherosclerosis, 2010 - Elsevier
OBJECTIVE: Adipocyte fatty acid-binding protein (FABP4) plasma levels are higher in type 2
diabetes (T2D). Endothelial dysfunction is also common in T2D. We have investigated the …

The fatty acid–binding protein-2 A54T polymorphism is associated with renal disease in patients with type 2 diabetes

LH Canani, C Capp, DPK Ng, SGL Choo, AL Maia… - Diabetes, 2005 - Am Diabetes Assoc
The intestinal fatty–acid binding protein-2 (FABP2) gene codes a protein responsible for the
absorption of long-chain fatty acids. To test whether FABP2 is a candidate gene for renal …

[HTML][HTML] Circulating fatty acid-binding protein 1 (FABP1) and nonalcoholic fatty liver disease in patients with type 2 diabetes mellitus

YC Lu, CC Chang, CP Wang, WC Hung… - … Journal of Medical …, 2020 - ncbi.nlm.nih.gov
Background: Fatty acid-binding protein 1 (FABP1)(also known as liver-type fatty acid-binding
protein or LFABP) is a protein that is mainly expressed in the liver, and is associated with …

Fatty acid-binding protein 4 mediates apoptosis via endoplasmic reticulum stress in mesangial cells of diabetic nephropathy

F Yao, Z Li, T Ehara, L Yang, D Wang, L Feng… - Molecular and cellular …, 2015 - Elsevier
Type 2 diabetes is characterized by hyperglycemia and deregulated lipid metabolism with
increased plasma non-esterified fatty acids (NEFA). Apoptosis of glomerular cells is a …

Fatty acid binding protein 4 is increased in metabolic syndrome and with thiazolidinedione treatment in diabetic patients

A Cabre, I Lazaro, J Girona, JM Manzanares… - Atherosclerosis, 2007 - Elsevier
OBJECTIVE: To study the role of FABP4 in the plasma of type 2 diabetic (T2D) subjects with
and without metabolic syndrome (MS) and the impact of thiazolidinedione (TZD) treatment …