The definition of functional heartburn has been refined over the years. It is currently
described, based upon Rome IV criteria, as typical heartburn symptoms in the presence of …

Functional heartburn (FH) is a functional gastro-intestinal disorder characterized by
symptoms of heartburn not related to gastro-esophageal reflux. The absence of evidence of …

Heartburn is among the most common gastrointestinal symptoms presenting to both
generalist physicians and gastroenterologists. Heartburn that does not respond to traditional …

Functional heartburn is considered one of the most common functional esophageal
disorders. The disorder is more common in young women and is associated with other …

Objectives Patients with heartburn and normal upper gastrointestinal endoscopy, normal
oesophageal acid exposure, no symptom-reflux association and who fail to respond to a …

Opinion statement Functional heartburn (FH) is a common disorder that accounts for 30% to
50% of the patients with nonerosive reflux disease. FH is composed from a heterogeneous …

Opinion statement Functional heartburn is defined as the presence of a retrosternal burning
sensation in the absence of pathologic gastroesophageal reflux. The underlying …

Heartburn is a symptom synonymous with gastroesophageal reflux disease (GERD), but as
our knowledge advances, we find that GERD is a more complex disorder than was originally …

Heartburn occurring at least once a month is reported by 10–20% of the general population
in the US [1], but very few sufferers actually seek medical help. Heartburn seems to be more …

Functional heartburn (FH) is defined as a functional esophageal disorder characterized by
symptoms of chronic heartburn with no apparent correlation to acid or nonacid reflux. In …