It is well known that certain non B-DNA structures, including G-quadruplexes, are key
elements that can regulate gene expression. Here, we explore the theory that DNA …

G-quadruplexes are four-stranded helical nucleic acid structures formed by guanine-rich
sequences. A considerable number of studies have revealed that these noncanonical …

Since DNA methylation alters the chromatin state and regulates gene expression,
elucidating the regulatory mechanisms of DNA methylation in response to environmental …

Four-stranded G-quadruplexes (G4s) are DNA secondary structures that can form in the
human genome. G4 structures have been detected in gene promoters and are associated …

In addition to the canonical double helix, DNA can fold into various other inter-and
intramolecular secondary structures. Although many such structures were long thought to be …

DNA and RNA can adopt various secondary structures. Four-stranded G-quadruplex (G4)
structures form through self-recognition of guanines into stacked tetrads, and considerable …

When we picture DNA, the image that comes immediately to mind is the iconic double helix.
However, the double helix is only the storage form for genetic information, and DNA takes on …

Unusual DNA structures such as four-stranded G-quadruplexes have been found to form in
vivo and to play regulatory roles. However, since DNA is normally present as chromatin, with …

Several decades elapsed between the first descriptions of G-quadruplex nucleic acid
structures (G4s) assembled in vitro and the emergence of experimental findings indicating …

Four‐stranded G‐rich DNA structures called G‐quadruplexes have been the subject of
increasing interest recently. Experimental and computational techniques have been used to …