Types of neurons in the human colonic myenteric plexus identified by multilayer immunohistochemical coding

BN Chen, A Humenick, WP Yew, RA Peterson… - Cellular and Molecular …, 2023 - Elsevier
Background and Aims Gut functions including motility, secretion, and blood flow are largely
controlled by the enteric nervous system. Characterizing the different classes of enteric …

Human enteric neurons: morphological, electrophysiological, and neurochemical identification

SE Carbone, V Jovanovska, K Nurgali… - …, 2014 - Wiley Online Library
Background Access to tissue, difficulties with dissection, and poor visibility of enteric ganglia
have hampered electrophysiological recordings of human enteric neurons. Here, we report …

Characterization of putative interneurons in the myenteric plexus of human colon

A Humenick, BN Chen, DA Wattchow… - …, 2021 - Wiley Online Library
Background The enteric nervous system contains multiple classes of neurons,
distinguishable by morphology, immunohistochemical markers, and projections; however …

Electrophysiological and morphological features of myenteric neurons of human colon revealed by intracellular recording and dye fills

WP Yew, A Humenick, BN Chen… - …, 2023 - Wiley Online Library
Background Ex vivo intracellular recordings and dye fills, combined with
immunohistochemistry, are a powerful way to analyze the enteric nervous system of …

Organization of the enteric nervous system in the human colon demonstrated by wholemount immunohistochemistry with special reference to the submucous plexus

T Wedel, U Roblick, J Gleiß, T Schiedeck… - Annals of Anatomy …, 1999 - Elsevier
To demonstrate the normal topography and structure of the enteric nervous system (ENS) in
the human colon, the colonic wall of patients (n= 10, mean age 66.3 years), who underwent …

Quantitative evaluation of neurons in the mucosal plexus of adult human intestines

K Kramer, ABM da Silveira, S Jabari, M Kressel… - Histochemistry and cell …, 2011 - Springer
The consequence of presence versus absence of mucosal neurons is not consistently
assessed. Here, we addressed two questions. First, based on resected gut specimens of 65 …

Quantification and neurochemical coding of the myenteric plexus in humans: No regional variation between the distal colon and rectum

KS Ng, NA Montes‐Adrian, DA Mahns… - …, 2018 - Wiley Online Library
Background It remains unclear whether regional variation exists in the human enteric
nervous system (ENS) ie, whether intrinsic innervation varies along the gut. Recent …

Identifying types of neurons in the human colonic enteric nervous system

S Brookes, N Chen, A Humenick, M Costa… - The Enteric Nervous …, 2023 - Springer
Distinguishing and characterising the different classes of neurons that make up a neural
circuit has been a long-term goal for many neuroscientists. The enteric nervous system is a …

Neurochemical profile of the myenteric plexus in the rat colorectal region

TV Kirov, DY Atanasova, NE Lazarov - The Anatomical Record, 2023 - Wiley Online Library
The enteric nervous system, a major subdivision of the autonomic nervous system, is known
for its neurochemical heterogeneity and complexity. The myenteric plexus, one of its two …

Morphological and neurochemical identification of enteric neurones with mucosal projections in the human small intestine

J Hens, JM Vanderwinden, MH De Laet… - Journal of …, 2001 - Wiley Online Library
Data on the axonal projections of enteric neurones in the human intestine are still scarce.
The present study aimed to identify the morphology and neurochemical coding of enteric …