Personalised virtual brain models in epilepsy
Individuals with drug-resistant focal epilepsy are candidates for surgical treatment as a
curative option. Before surgery can take place, the patient must have a presurgical …
curative option. Before surgery can take place, the patient must have a presurgical …
Virtual epileptic patient brain modeling: Relationships with seizure onset and surgical outcome
J Makhalova, S Medina Villalon, H Wang… - …, 2022 - Wiley Online Library
Objective The virtual epileptic patient (VEP) is a large‐scale brain modeling method based
on virtual brain technology, using stereoelectroencephalography (SEEG), anatomical data …
on virtual brain technology, using stereoelectroencephalography (SEEG), anatomical data …
Delineating epileptogenic networks using brain imaging data and personalized modeling in drug-resistant epilepsy
HE Wang, M Woodman, P Triebkorn… - Science Translational …, 2023 - science.org
Precise estimates of epileptogenic zone networks (EZNs) are crucial for planning
intervention strategies to treat drug-resistant focal epilepsy. Here, we present the virtual …
intervention strategies to treat drug-resistant focal epilepsy. Here, we present the virtual …
Individual brain structure and modelling predict seizure propagation
Abstract See Lytton (doi: 10.1093/awx018) for a scientific commentary on this article. Neural
network oscillations are a fundamental mechanism for cognition, perception and …
network oscillations are a fundamental mechanism for cognition, perception and …
[HTML][HTML] The Bayesian Virtual Epileptic Patient: A probabilistic framework designed to infer the spatial map of epileptogenicity in a personalized large-scale brain …
Despite the importance and frequent use of Bayesian frameworks in brain network modeling
for parameter inference and model prediction, the advanced sampling algorithms …
for parameter inference and model prediction, the advanced sampling algorithms …
[HTML][HTML] The virtual epileptic patient: individualized whole-brain models of epilepsy spread
Individual variability has clear effects upon the outcome of therapies and treatment
approaches. The customization of healthcare options to the individual patient should …
approaches. The customization of healthcare options to the individual patient should …
Predicting neurosurgical outcomes in focal epilepsy patients using computational modelling
Abstract See Eissa and Schevon (doi: 10.1093/aww332) for a scientific commentary on this
article. Surgery can be a last resort for patients with intractable, medically refractory epilepsy …
article. Surgery can be a last resort for patients with intractable, medically refractory epilepsy …
Brain imaging in the assessment for epilepsy surgery
JS Duncan, GP Winston, MJ Koepp… - The Lancet …, 2016 - thelancet.com
Brain imaging has a crucial role in the presurgical assessment of patients with epilepsy.
Structural imaging reveals most cerebral lesions underlying focal epilepsy. Advances in MRI …
Structural imaging reveals most cerebral lesions underlying focal epilepsy. Advances in MRI …
[HTML][HTML] Optimization of surgical intervention outside the epileptogenic zone in the Virtual Epileptic Patient (VEP)
Studies to improve the efficacy of epilepsy surgery have focused on better refining the
localization of the epileptogenic zone (EZ) with the aim of effectively resecting it. However, in …
localization of the epileptogenic zone (EZ) with the aim of effectively resecting it. However, in …
[HTML][HTML] Identifying spatio-temporal seizure propagation patterns in epilepsy using Bayesian inference
Focal drug resistant epilepsy is a neurological disorder characterized by seizures caused by
abnormal activity originating in one or more regions together called as epileptogenic zone …
abnormal activity originating in one or more regions together called as epileptogenic zone …