Chronic pancreatitis (CP) is a disease characterized by inflammatory recurrence that
accompanies the development of pancreatic fibrosis. As the mystery of CP pathogenesis is …

In the complex progression of fibrosis in chronic pancreatitis, pancreatic stellate cells (PSCs)
emerge as central figures. These cells, initially in a dormant state characterized by the …

Chronic pancreatitis (CP) is a precancerous illness linked to pancreatic ductal
adenocarcinoma (PDAC), although the evolutionary mechanism is uncertain. CP is …

Chronic pancreatitis is a common disorder of which the underlying pathogenic mechanisms
still are incompletely understood. In the last decade, increasing evidence has shown that …

Significance: Prominent fibrosis is a major histological feature of chronic pancreatitis, a
progressive necroinflammatory condition of the pancreas, most commonly associated with …

Chronic pancreatitis (CP) is characterized by progressive fibrosis, pain and/or loss of
exocrine and endocrine functions. Recent in vitro and in vivo experiments have proven …

While the morphology and function of cells of the exocrine and endocrine pancreas have
been studied over several centuries, one important cell type in the gland, the pancreatic …

Pancreatic fibrosis is a characteristic feature of chronic pancreatitis and of desmoplastic
reaction associated with pancreatic cancer. For over a decade, there has been accumulating …

Chronic pancreatitis (CP) is a fibro-inflammatory disease leading to pain, maldigestion, and
pancreatic insufficiency. No therapeutic options exist due to a limited understanding of the …

Over a decade, there is accumulating evidence that activated pancreatic stellate cells
(PSCs) play a pivotal role in the development of pancreatic fibrosis. In response to …