Chemokines were originally described as chemotactic cytokines involved in leukocyte
trafficking. Research over the last decade, however, has shown that chemokine receptors …

Chemokines are a large family of small secreted proteins (8–14 kDa) associated with the
trafficking of leukocytes in physiological immunosurveillance as well as inflammatory cell …

Chemokines represent key factors in the outburst of the immune response, by activating and
directing the leukocyte traffic, both in lymphopoiesis and in immune surveillance …

Chemokines are small secreted proteins that chemoattract and activate immune and non-
immune cells both in vivo and in vitro. Besides their well-established role in the immune …

Chemokines in the brain have been recognised as essential elements in neurodegenerative
diseases and related neuroinflammation. Recent studies suggest that in addition to the …

Chemokines are small secreted proteins that are essential for the recruitment and activation
of specific leukocyte subsets at sites of inflammation and for the development and …

Whereas chemokines are well known for their ability to induce cell migration, only recently it
became evident that chemokines also control a variety of other cell functions and are …

Chemokines and their receptors have principal roles in leukocyte trafficking under normal
physiological and pathological conditions. The differential expression of the chemokine …

Alzheimer's disease (AD) is the most common cause of dementia in the elderly, and the
fourth leading cause of death in the United States. Its pathological changes include amyloid …

Chemokines were detected by virtue of chemotactic effects toward neutrophils in the late
1970s. During subsequent decades, it has become clear that their primordial role in …