Maternal Ybx1 safeguards zebrafish oocyte maturation and maternal-to-zygotic transition by repressing global translation

J Sun, L Yan, W Shen, A Meng - Development, 2018 - journals.biologists.com
Maternal mRNAs and proteins dictate early embryonic development before zygotic genome
activation. In the absence of transcription, elaborate control of maternal mRNA translation is …

Proteomic analysis of zebrafish folliculogenesis identifies YB-1 (Ybx1/ybx1) as a potential gatekeeping molecule controlling early ovarian folliculogenesis

ESW Lau, B Zhu, MA Sun, SM Ngai… - Biology of …, 2023 - academic.oup.com
As in mammals, ovarian folliculogenesis in teleosts also consists of two phases: the primary
growth (PG) and secondary growth (SG) phases, which are analogous to the preantral and …

YBX1 mediates alternative splicing and maternal mRNA decay during pre-implantation development

M Deng, B Chen, Z Liu, Y Wan, D Li, Y Yang, F Wang - Cell & Bioscience, 2022 - Springer
Background In mammals, maternal gene products decay and zygotic genome activation
(ZGA) during maternal to zygotic transition (MZT) is critical for the early embryogenesis. Y …

Y‐box binding protein 1 influences zygotic genome activation by regulating N6‐methyladenosine in porcine embryos

WJ Jiang, MH Sun, XH Li, SH Lee… - Journal of Cellular …, 2023 - Wiley Online Library
Y‐box binding protein 1 (YBX1) is a member of the family of DNA‐and RNA‐binding
proteins that play crucial roles in multiple aspects, including RNA stabilization, translational …

RNA 5-methylcytosine facilitates the maternal-to-zygotic transition by preventing maternal mRNA decay

Y Yang, L Wang, X Han, WL Yang, M Zhang, HL Ma… - Molecular cell, 2019 - cell.com
The maternal-to-zygotic transition (MZT) is a conserved and fundamental process during
which the maternal environment is converted to an environment of embryonic-driven …

Knockdown of Y-box binding protein 1 induces autophagy in early porcine embryos

WJ Jiang, SH Lee, G Heo, HJ Chung… - Frontiers in Cell and …, 2023 - frontiersin.org
Y-box binding protein 1 (YBX1) plays important roles in RNA stabilization, translation,
transcriptional regulation, and mitophagy. However, its effects on porcine preimplantation …

Drosophila YBX1 homolog YPS promotes ovarian germ line stem cell development by preferentially recognizing 5-methylcytosine RNAs

F Zou, R Tu, B Duan, Z Yang, Z Ping… - Proceedings of the …, 2020 - National Acad Sciences
5-Methylcytosine (m5C) is a RNA modification that exists in tRNAs and rRNAs and was
recently found in mRNAs. Although it has been suggested to regulate diverse biological …

Translation repression by maternal RNA binding protein Zar1 is essential for early oogenesis in zebrafish

L Miao, Y Yuan, F Cheng, J Fang, F Zhou… - …, 2017 - journals.biologists.com
A large amount of maternal RNA is deposited in oocytes and is reserved for later
development. Control of maternal RNA translation during oocyte maturation has been …

Spatio-temporal regulation of Wnt and retinoic acid signaling by tbx16/spadetail during zebrafish mesoderm differentiation

RL Mueller, C Huang, RK Ho - BMC genomics, 2010 - Springer
Background A complex network of signaling pathways and transcription factors regulates
vertebrate mesoderm development. Zebrafish mutants provide a powerful tool for examining …

[HTML][HTML] Ybx1 fine-tunes PRC2 activities to control embryonic brain development

MK Evans, Y Matsui, B Xu, C Willis, J Loome… - Nature …, 2020 - nature.com
Chromatin modifiers affect spatiotemporal gene expression programs that underlie
organismal development. The Polycomb repressive complex 2 (PRC2) is a crucial chromatin …