Maternal Ybx1 safeguards zebrafish oocyte maturation and maternal-to-zygotic transition by repressing global translation
Maternal mRNAs and proteins dictate early embryonic development before zygotic genome
activation. In the absence of transcription, elaborate control of maternal mRNA translation is …
activation. In the absence of transcription, elaborate control of maternal mRNA translation is …
Proteomic analysis of zebrafish folliculogenesis identifies YB-1 (Ybx1/ybx1) as a potential gatekeeping molecule controlling early ovarian folliculogenesis
As in mammals, ovarian folliculogenesis in teleosts also consists of two phases: the primary
growth (PG) and secondary growth (SG) phases, which are analogous to the preantral and …
growth (PG) and secondary growth (SG) phases, which are analogous to the preantral and …
YBX1 mediates alternative splicing and maternal mRNA decay during pre-implantation development
Background In mammals, maternal gene products decay and zygotic genome activation
(ZGA) during maternal to zygotic transition (MZT) is critical for the early embryogenesis. Y …
(ZGA) during maternal to zygotic transition (MZT) is critical for the early embryogenesis. Y …
Y‐box binding protein 1 influences zygotic genome activation by regulating N6‐methyladenosine in porcine embryos
WJ Jiang, MH Sun, XH Li, SH Lee… - Journal of Cellular …, 2023 - Wiley Online Library
Y‐box binding protein 1 (YBX1) is a member of the family of DNA‐and RNA‐binding
proteins that play crucial roles in multiple aspects, including RNA stabilization, translational …
proteins that play crucial roles in multiple aspects, including RNA stabilization, translational …
RNA 5-methylcytosine facilitates the maternal-to-zygotic transition by preventing maternal mRNA decay
The maternal-to-zygotic transition (MZT) is a conserved and fundamental process during
which the maternal environment is converted to an environment of embryonic-driven …
which the maternal environment is converted to an environment of embryonic-driven …
Knockdown of Y-box binding protein 1 induces autophagy in early porcine embryos
WJ Jiang, SH Lee, G Heo, HJ Chung… - Frontiers in Cell and …, 2023 - frontiersin.org
Y-box binding protein 1 (YBX1) plays important roles in RNA stabilization, translation,
transcriptional regulation, and mitophagy. However, its effects on porcine preimplantation …
transcriptional regulation, and mitophagy. However, its effects on porcine preimplantation …
Drosophila YBX1 homolog YPS promotes ovarian germ line stem cell development by preferentially recognizing 5-methylcytosine RNAs
5-Methylcytosine (m5C) is a RNA modification that exists in tRNAs and rRNAs and was
recently found in mRNAs. Although it has been suggested to regulate diverse biological …
recently found in mRNAs. Although it has been suggested to regulate diverse biological …
Translation repression by maternal RNA binding protein Zar1 is essential for early oogenesis in zebrafish
A large amount of maternal RNA is deposited in oocytes and is reserved for later
development. Control of maternal RNA translation during oocyte maturation has been …
development. Control of maternal RNA translation during oocyte maturation has been …
Spatio-temporal regulation of Wnt and retinoic acid signaling by tbx16/spadetail during zebrafish mesoderm differentiation
RL Mueller, C Huang, RK Ho - BMC genomics, 2010 - Springer
Background A complex network of signaling pathways and transcription factors regulates
vertebrate mesoderm development. Zebrafish mutants provide a powerful tool for examining …
vertebrate mesoderm development. Zebrafish mutants provide a powerful tool for examining …
[HTML][HTML] Ybx1 fine-tunes PRC2 activities to control embryonic brain development
Chromatin modifiers affect spatiotemporal gene expression programs that underlie
organismal development. The Polycomb repressive complex 2 (PRC2) is a crucial chromatin …
organismal development. The Polycomb repressive complex 2 (PRC2) is a crucial chromatin …