Metabolic disorders and diabetes (DM) impact more than five hundred million individuals
throughout the world and are insidious in onset, chronic in nature, and yield significant …

Wnt signaling is an ancient and evolutionarily conserved pathway with fundamental roles in
the development of adipose tissues. Roles of this pathway in mesenchymal stem cell fate …

Diabetes mellitus affects almost 350 million individuals throughout the globe resulting in
significant morbidity and mortality. Of further concern is the growing population of individuals …

A fundamental question in cell biology underlies how nutrients are regenerated to maintain
and renew tissues. Physiologically, the canonical Wnt signaling is a vital pathway for cell …

Chronic diseases account for approximately 45% of all deaths in developed countries and
are particularly prevalent in countries with the most sophisticated and robust public health …

In this issue of Diabetologia, T. Jin [1] reviews our current understanding of how WNT
signalling can be related to type 2 diabetes. The great interest in this topic stems from the …

Wnt signaling molecules are associated with obesity, hyperlipidemia and type 2 diabetes
(T2D). Here, we show that two Wnt proteins, WNT3a and WNT4, are specifically secreted by …

At the cellular level, the biological processes of cell proliferation, growth arrest,
differentiation and apoptosis are all tightly coupled to appropriate alterations in metabolic …

The release of reactive oxygen species (ROS) and the generation of oxidative stress are
considered critical factors for the pathogenesis of diabetes mellitus (DM), a disorder that is …

Type 2 diabetes mellitus (T2DM) is a metabolic disorder that is characterized by functional
defects in glucose metabolism and insulin secretion. Its complex etiology and multifaceted …