Detection of circulating antigen of Dirofilaria immitis has been a mainstay of identifying
heartworm infection in clinical practice for the past three decades. Several validated …

Patient-side test kits for detecting antigenemia in dogs associated with sexually mature
female heartworms (Dirofilaria immitis) have been available for three decades, and these …

Background The diagnosis and management of canine heartworm disease is a growing
concern for shelter veterinarians. Although the accuracy of commercial antigen test kits has …

Background To evaluate whether heated serum allows for earlier detection of Dirofilaria
immitis antigen, dogs with experimental D. immitis infections underwent weekly blood …

In the last two decades, reports of canine heartworm (HW) infection have increased even in
non-endemic areas, with a large variability in prevalence data due to the diagnostic strategy …

Abstract Background Diagnosis of Dirofilaria immitis infection in cats is complicated by the
difficulty associated with reliable detection of antigen in feline blood and serum samples …

Background Current recommendations for diagnosis of Dirofilaria immitis infection in dogs
rely on the detection of antigen produced largely by adult females coupled with the …

Background Dogs with chronic inflammation, including those with heartworm being
managed with macrocyclic lactones and doxycycline (slow kill, SK), may develop immune …

Background Antigen testing is routinely used to diagnose canine Dirofilaria immitis
infections. Immune complex dissociation (ICD) methods, which were employed in the …

Understanding diagnosis of heartworm disease in the context of animal shelters' needs and
expectations is crucial for developing guidelines that specifically address the unique shelter …