Strain-transcending neutralization of malaria parasite by antibodies against Plasmodium falciparum enolase
S Dutta, A Tewari, C Balaji, R Verma, A Moitra… - Malaria Journal, 2018 - Springer
Background Plasmodium enolase is a target for the growth neutralizing antibodies.
Interestingly, the three invasive stages ie sporozoites, merozoites, and ookinetes express …
Interestingly, the three invasive stages ie sporozoites, merozoites, and ookinetes express …
Immunogenicity and protective potential of a Plasmodium spp. enolase peptide displayed on archaeal gas vesicle nanoparticles
Background Plasmodium falciparum enolase has been shown to localize on the surface of
merozoites and ookinetes. Immunization of mice with recombinant Plasmodium enolase …
merozoites and ookinetes. Immunization of mice with recombinant Plasmodium enolase …
Plasmodium falciparum enolase: stage-specific expression and sub-cellular localization
I Pal Bhowmick, N Kumar, S Sharma, I Coppens… - Malaria journal, 2009 - Springer
Background In an earlier study, it was observed that the vaccination with Plasmodium
falciparum enolase can confer partial protection against malaria in mice. Evidence has also …
falciparum enolase can confer partial protection against malaria in mice. Evidence has also …
Protective Properties and Surface Localization of Plasmodium falciparum Enolase
The enolase protein of the human malarial parasite Plasmodium falciparum has recently
been characterized. Apart from its glycolytic function, enolase has also been shown to …
been characterized. Apart from its glycolytic function, enolase has also been shown to …
[PDF][PDF] Generation and characterisation of monoclonal antibodies specific to Plasmodium falciparum enolase
I Pal-Bhowmick, HK Vora, J Roy… - Journal of Vector …, 2006 - researchgate.net
Background & objectives: Glycolysis is the sole source of energy for the intraerythrocytic
stages of Plasmodium falciparum, making glycolytic enzymes putative therapeutic targets …
stages of Plasmodium falciparum, making glycolytic enzymes putative therapeutic targets …
Surface-expressed enolases of Plasmodium and other pathogens
AK Ghosh, M Jacobs-Lorena - Memorias do Instituto Oswaldo Cruz, 2011 - SciELO Brasil
Enolase is the eighth enzyme in the glycolytic pathway, a reaction that generates ATP from
phosphoenol pyruvate in cytosolic compartments. Enolase is essential, especially for …
phosphoenol pyruvate in cytosolic compartments. Enolase is essential, especially for …
EWGWS insert in Plasmodium falciparum ookinete surface enolase is involved in binding of PWWP containing peptides: implications to mosquito midgut invasion by …
D Mukherjee, P Mishra, M Joshi, PK Thakur… - Insect biochemistry and …, 2016 - Elsevier
There are multiple stages in the life cycle of Plasmodium that invade host cells. Molecular
machinery involved is such host–pathogen interactions constitute excellent drug targets …
machinery involved is such host–pathogen interactions constitute excellent drug targets …
Effect of deletion of a plant like pentapeptide insert on kinetic, structural and immunological properties of enolase from Plasmodium falciparum
HK Vora, FR Shaik, I Pal-Bhowmick, R Mout… - Archives of biochemistry …, 2009 - Elsevier
Plasmodium falciparum enolase (Pfen) is of photosynthetic lineage as evident from the
presence of a plant like pentapeptide insert 104EWGWS108 in a highly conserved surface …
presence of a plant like pentapeptide insert 104EWGWS108 in a highly conserved surface …
Sub-cellular localization and post-translational modifications of the Plasmodium yoelii enolase suggest moonlighting functions
I Pal-Bhowmick, HK Vora, GK Jarori - Malaria Journal, 2007 - Springer
Abstract Background Enolase (2-Phospho-D-glycerate hydrolase; EC 4.2. 1.11) is one of the
glycolytic enzymes, whose levels are highly elevated in malaria parasite infected red blood …
glycolytic enzymes, whose levels are highly elevated in malaria parasite infected red blood …
Differential susceptibility of Plasmodium falciparum versus yeast and mammalian enolases to dissociation into active monomers
In the past, several unsuccessful attempts have been made to dissociate homodimeric
enolases into their active monomeric forms. The main objective of these studies had been to …
enolases into their active monomeric forms. The main objective of these studies had been to …