GM3, the simplest ganglioside, modulates cell adhesion, proliferation and differentiation in
the central nervous system and exogenously added GM3 regulates cell–cell and cell …

The simple ganglioside GM3 inhibits proliferation and induces apoptosis in proliferating
immature rodent CNS cells. To determine whether GM3 influenced the expansion of human …

Control of cell proliferation and cell survival is critical during development of the vertebrate
central nervous system (CNS). Much of the cell death seen during early stages of CNS …

Progression of malignant brain tumors is dependent upon vascularity and is associated with
altered ganglioside composition and distribution. Evidence is reviewed showing that the …

We have found that an increase in the ganglioside GM3 is a prerequisite for the induction of
terminal differentiation, culminating in death by apoptosis, of human colonic carcinoma cells …

The definitive role of ganglioside GM2 in mediating tumor-induced growth and progression
is still unknown. Here we report a novel role of ganglioside GM2 in mediating tumor cell …

Sialic acid-containing glycosphingolipids, gangliosides, are considered as cancer
associated antigens in neuro-ectoderm-derived tumors such as melanomas and …

Ganglioside GD3 is overexpressed in many types of tumors and may be associated with
tumor progression and the development of metastatic potential. In our previous study (G …

This work describes the in vivo expression and distribution of glioma‐associated
gangliosides (GD3, GM2, 3′‐isoLM1) in a novel human brain tumour nude rat xenograft …

Ganglioside GM3 is well known as a tumor-associated carbohydrate antigen on several
types of tumors. Many studies have demonstrated that GM3 plays roles in cells proliferation …