[HTML][HTML] Novel approaches to tuberculosis vaccine development

SHE Kaufmann, J Weiner, CF von Reyn - International Journal of Infectious …, 2017 - Elsevier
Tuberculosis (TB) remains the deadliest infectious disease. The widely used bacille
Calmette–Guérin (BCG) vaccine offers only limited protection against TB. New vaccine …

Vaccines against Tuberculosis: Where Are We Now?

S Srivastava, S Dey, S Mukhopadhyay - Vaccines, 2023 - mdpi.com
Tuberculosis (TB) is among the top 10 leading causes of death in low-income countries.
Statistically, TB kills more than 30,000 people each week and leads to more deaths than any …

Novel vaccination strategies against tuberculosis

P Andersen, SHE Kaufmann - Cold Spring …, 2014 - perspectivesinmedicine.cshlp.org
The tuberculosis (TB) pandemic continues to rampage despite widespread use of the BCG
(Bacillus Calmette–Guérin) vaccine. Novel vaccination strategies are urgently needed to …

Tuberculosis vaccines in clinical trials

R Rowland, H McShane - Expert review of vaccines, 2011 - Taylor & Francis
Effective prophylactic and/or therapeutic vaccination is a key strategy for controlling the
global TB epidemic. The partial effectiveness of the existing TB vaccine, bacille Calmette …

An overview of the development of new vaccines for tuberculosis

E Whitlow, AS Mustafa, SNM Hanif - Vaccines, 2020 - mdpi.com
Currently, there is only one licensed vaccine against tuberculosis (TB), the Bacillus Calmette–
Guérin (BCG). Despite its protective efficacy against TB in children, BCG has failed to protect …

Tuberculosis vaccine development: progress in clinical evaluation

SB Sable, JE Posey, TJ Scriba - Clinical microbiology reviews, 2019 - Am Soc Microbiol
Tuberculosis (TB) is the leading killer among all infectious diseases worldwide despite
extensive use of the Mycobacterium bovis bacille Calmette-Guérin (BCG) vaccine. A safer …

The current status, challenges, and future developments of new tuberculosis vaccines

W Gong, Y Liang, X Wu - Human vaccines & immunotherapeutics, 2018 - Taylor & Francis
Mycobacterium tuberculosis complex causes tuberculosis (TB), one of the top 10 causes of
death worldwide. TB results in more fatalities than multi-drug resistant (MDR) HIV strain …

Tuberculosis vaccines—an update.

P Andersen - Nature Reviews Microbiology, 2007 - nature.com
The current tuberculosis (TB) vaccine Mycobacterium bovis bacillus Calmette-Guérin (BCG)
is the most widely used vaccine worldwide, but it does not prevent the establishment of …

The dream of a vaccine against tuberculosis; new vaccines improving or replacing BCG?

C Martin - European Respiratory Journal, 2005 - Eur Respiratory Soc
In the last 10 yrs, work with experimental laboratory models has developed many new
vaccine candidates against tuberculosis (TB). They include subunit vaccines, modified …

[HTML][HTML] Vaccination against tuberculosis: revamping BCG by molecular genetics guided by immunology

SHE Kaufmann - Frontiers in immunology, 2020 - frontiersin.org
Tuberculosis (TB) remains a major health threat. Although a vaccine has been available for
almost 100 years termed Bacille Calmette-Guérin (BCG), it is insufficient and better vaccines …