Abstract Grainyhead-like 2 (GRHL2), one of the three homologs of Drosophila grainyhead,
contributes to epithelial morphogenesis and differentiation. Dysregulation of GRHL2 has …

The transcription factor grainyhead‐like 2 (GRHL2) plays a crucial role in various
developmental processes. Although GRHL2 recently has attracted considerable interest in …

GRHL2 was implicated in regulating cancer development. Our previous study demonstrated
that knockdown GRHL2 in colorectal cancer (CRC) cells inhibited cell proliferation by …

Abstract Grainyhead-like 2 (GRHL2) is one of the three mammalian homologues of
Drosophila Grainyhead involved in epithelial morphogenesis. We recently showed that …

In mammals, the grainyhead-like transcription factor (GRHL) family is composed of three
nuclear proteins that are responsible for driving epithelial cell fate: GRHL1, GRHL2, and …

Abstract Grainyhead‑like 2 (GRHL2) is a transcription factor that suppresses epithelial‑to‑
mesenchymal transition (EMT). It has been previously shown that GRHL2 can confer both …

Among the transcription factors that are conserved across phylogeny, the grainyhead family
holds vital roles in driving the epithelial cell fate. In Drosophila, the function of grainyhead …

Abstract Grainyhead-like 1 (GRHL1) is a transcription factor involved in embryonic
development. However, little is known about the biological functions of GRHL1 in cancer. In …

Grainyhead-like (GRHL) factors are essential, highly conserved transcription factors (TFs)
that regulate processes common to both natural cellular behaviours during embryogenesis …

Summary The Grainyhead-like 3 (GRHL3) is involved in epidermal barrier formation, neural
tube closure and wound repair. Previous studies have suggested that GRHL3 has been …