Pilot study of resveratrol in older adults with impaired glucose tolerance

JP Crandall, V Oram, G Trandafirescu… - … Series A: Biomedical …, 2012 - academic.oup.com
Background. Resveratrol, a plant-derived polyphenol, has shown promising effects on
insulin sensitivity and glucose tolerance in animal models and is also reported to have …

Resveratrol improves vascular function and mitochondrial number but not glucose metabolism in older adults

RM Pollack, N Barzilai, V Anghel… - … Series A: Biomedical …, 2017 - academic.oup.com
Background Resveratrol, a plant-derived polyphenol, has been reported to improve glucose
metabolism and vascular function and to extend life span in animal models, but studies in …

Safety and metabolic outcomes of resveratrol supplementation in older adults: results of a twelve-week, placebo-controlled pilot study

SD Anton, C Embry, M Marsiske, X Lu, H Doss… - Experimental …, 2014 - Elsevier
Resveratrol has been found to have potent antioxidant, anti-inflammatory, and
anticarcinogenic effects. The safety and efficacy of resveratrol supplementation in older …

Influence of age and dose on the effect of resveratrol for glycemic control in type 2 diabetes mellitus: Systematic review and meta-analysis

BI García-Martínez, M Ruiz-Ramos, J Pedraza-Chaverri… - Molecules, 2022 - mdpi.com
Background: Several clinical trials have suggested that resveratrol has hypoglycemic
properties; however, there are other studies in which such an effect has not been observed …

Resveratrol as add-on therapy in subjects with well-controlled type 2 diabetes: a randomized controlled trial

S Timmers, M De Ligt, E Phielix… - Diabetes …, 2016 - Am Diabetes Assoc
OBJECTIVE To determine whether resveratrol supplementation can improve insulin
sensitivity and promote overall metabolic health on top of standard diabetes care …

[HTML][HTML] Effect of resveratrol on glucose control and insulin sensitivity: a meta-analysis of 11 randomized controlled trials

K Liu, R Zhou, B Wang, MT Mi - The American journal of clinical nutrition, 2014 - Elsevier
Background: The results of human clinical trials investigating the effects of resveratrol on
glucose control and insulin sensitivity are inconsistent. Objective: We aimed to quantitatively …

[HTML][HTML] No effect of resveratrol supplementation after 6 months on insulin sensitivity in overweight adults: A randomized trial

M de Ligt, M Bergman, RM Fuentes, H Essers… - The American journal of …, 2020 - Elsevier
Background Effects of resveratrol on metabolic health have been studied in several short-
term human clinical trials, with conflicting results. Next to dose, the duration of the clinical …

Challenges of translating basic research into therapeutics: resveratrol as an example

JM Smoliga, O Vang, JA Baur - Journals of Gerontology Series A …, 2012 - academic.oup.com
Basic science literature abounds with molecules that promise to ameliorate almost any
disease, from curing cancer to slowing the aging process itself. However, most of these …

Higher dose of resveratrol elevated cardiovascular disease risk biomarker levels in overweight older adults–A pilot study

RT Mankowski, L You, TW Buford… - Experimental …, 2020 - Elsevier
Older adults are at high risk of developing cardiovascular disease (CVD). Pre-clinical
studies indicate that resveratrol (RSV), a polyphenol commonly found in grapes and red …

Resveratrol supplementation: where are we now and where should we go?

MG Novelle, D Wahl, C Diéguez, M Bernier… - Ageing research …, 2015 - Elsevier
Pre-clinical findings have provided mounting evidence that resveratrol, a dietary polyphenol,
may confer health benefits and protect against a variety of medical conditions and age …