Autism spectrum disorder (ASD) is a complicated, heterogeneous disorder characterized by
social interaction deficits and repetitive stereotypical behaviors. Neuroinflammation and …

Depression is a chronic, severe, and often life-threatening disease accompanied with
impaired neurogenesis. Evidence showed that neuroinflammation played a key role in the …

Multiple sclerosis (MS) is a systemic inflammatory illness of the central nervous system that
involves demyelinating lesions in the myelin-rich white matter and pathology in the grey …

Aim This study aimed to investigate the effect of icariin (referred as ICA) on Alzheimer's
disease (AD) model through endoplasmic reticulum (ER) stress pathway. Main methods …

Background: Alzheimer's disease (AD) is the most common neurodegenerative disorder that
also involves neuroinflammation in addition to many other features. Icariin (ICA) as one of …

Autism spectrum disorder (ASD) is diagnosed by core symptoms including impaired social
communication and the presence of repetitive and stereotypical behaviors. There is also …

Abstract Ethnopharmacological relevance Epimedium brevicornu Maxim. is a traditional
medicinal Chinese herb that is enriched with flavonoids, which have remarkably high …

Effective therapeutic drugs for prevent or reverse the pathobiology of Alzheimer's disease
(AD) have not been developed. Icariin (ICA), a prenylated flavonol glycoside derived from …

Parkinson's disease (PD) is one of the most common neurodegenerative diseases
characterized with a gradual loss of midbrain substantia nigra (SN) dopamine (DA) neurons …

Postnatal immune activation (PIA) can affect normal brain development and increase the risk
of behavioral abnormalities in later life, including depressive-like behavior. Therefore, there …