In Situ Cross-Linkable Hyaluronic–Ferulic Acid Conjugate Containing Bucladesine Nanoparticles Promotes Neural Regeneration after Spinal Cord Injury

F Sorouri, P Hosseini, M Sharifzadeh… - … Applied Materials & …, 2023 - ACS Publications
Dysfunctional clinical outcomes following spinal cord injury (SCI) result from glial scar
formation, leading to the inhibition of new axon growth and impaired regeneration …

[HTML][HTML] An injectable and self-healing hydrogel with controlled release of curcumin to repair spinal cord injury

J Luo, X Shi, L Li, Z Tan, F Feng, J Li, M Pang, X Wang… - Bioactive materials, 2021 - Elsevier
The harsh local micro-environment following spinal cord injury (SCI) remains a great
challenge for neural regeneration. Local reconstitution of a favorable micro-environment by …

A bioinspired injectable, adhesive, and self‐healing hydrogel with dual hybrid network for neural regeneration after spinal cord injury

L Xiao, P Xie, J Ma, K Shi, Y Dai, M Pang… - Advanced …, 2023 - Wiley Online Library
Hydrogel‐based regenerated scaffolds show promise as a platform for neural regeneration
following spinal cord injury (SCI). Nevertheless, the persistent problem of poor mechanical …

An anti-inflammatory peptide and brain-derived neurotrophic factor-modified hyaluronan-methylcellulose hydrogel promotes nerve regeneration in rats with spinal …

Z He, H Zang, L Zhu, K Huang, T Yi… - International Journal …, 2019 - Taylor & Francis
Background Traumatic spinal cord injury (SCI) causes neuronal death, demyelination,
axonal degeneration, inflammation, glial scar formation, and cystic cavitation resulting in …

Injectable hydroxyphenyl derivative of hyaluronic acid hydrogel modified with RGD as scaffold for spinal cord injury repair

K Zaviskova, D Tukmachev, J Dubisova… - … Research Part A, 2018 - Wiley Online Library
Hydrogel scaffolds which bridge the lesion, together with stem cell therapy represent a
promising approach for spinal cord injury (SCI) repair. In this study, a hydroxyphenyl …

A conductive dual-network hydrogel composed of oxidized dextran and hyaluronic-hydrazide as BDNF delivery systems for potential spinal cord injury repair

F Huang, T Chen, J Chang, C Zhang, F Liao… - International Journal of …, 2021 - Elsevier
Spinal cord injury (SCI) often causes neuronal death and axonal degeneration. In this study,
we report a new strategy for preparing injectable and conductive polysaccharides-based …

A thermosensitive heparin-poloxamer hydrogel bridges aFGF to treat spinal cord injury

Q Wang, Y He, Y Zhao, H Xie, Q Lin, Z He… - … Applied Materials & …, 2017 - ACS Publications
Acidic fibroblast growth factor (aFGF) exerts a protective effect on spinal cord injury (SCI) but
is limited by the lack of physicochemical stability and the ability to cross the blood spinal …

Cooperative assembly of a designer peptide and silk fibroin into hybrid nanofiber gels for neural regeneration after spinal cord injury

F Feng, X Song, Z Tan, Y Tu, L Xiao, P Xie, Y Ma… - Science …, 2023 - science.org
Local reconstruction of a permissive environment with biomaterials is a promising strategy to
treat spinal cord injury (SCI). We reported a hybrid hydrogel fabricated from a small …

A multi-modal delivery strategy for spinal cord regeneration using a composite hydrogel presenting biophysical and biochemical cues synergistically

W Man, S Yang, Z Cao, J Lu, X Kong, X Sun, L Zhao… - Biomaterials, 2021 - Elsevier
Extensive tissue engineering studies have supported the enhanced spinal cord
regeneration by implantable scaffolds loaded with bioactive cues. However, scaffolds with …

A single dose of thermal-sensitive biodegradable hybrid hydrogel promotes functional recovery after spinal cord injury

XL Li, M Wu, L Gu, YT Ren, M Mu, YL Wang… - Applied Materials …, 2019 - Elsevier
Sensorimotor functional recovery after spinal cord injury (SCI) is still a large challenge in the
clinic. Cabazitaxel (Cab) is a microtubule inhibitor approved by the FDA in 2010 for …