Evaluating Hypericin as a Therapeutic Agent Against Neisseria gonorrhoeae

IV Ferrari - 2024 - preprints.org
Neisseria gonorrhoeae is a bacterium that causes the sexually transmitted infection
gonorrhea. This study employed molecular docking simulations to investigate potential …

Exploring Hypericin as a Potential Modulator of Key Targets in Escherichia coli

IV Ferrari - 2024 - preprints.org
This study employs molecular docking techniques to investigate a spectrum of targets within
Escherichia coli (E. coli), with a specific focus on four key proteins: Beta-lactamase, MccE …

Investigation into the Interaction between Penicillin‐Resistant and Penicillin‐Susceptible Gonococcal Penicillin‐Binding Protein 2 and Target Phenolic Ligands …

S Yakobi, L Zuma, O Pooe - Advances in Pharmacological and …, 2024 - Wiley Online Library
Gonococcal infections present a notable public health issue, and the major approach for
treatment involves using β‐lactam antibiotics that specifically target penicillin‐binding …

Identification of novel efflux pump inhibitors for Neisseria gonorrhoeae via multiple ligand-based pharmacophores, e-pharmacophore, molecular docking, density …

N Jain, MF Sk, A Mishra, P Kar, A Kumar - Computational Biology and …, 2022 - Elsevier
Neisseria gonorrhoeae have progressively developed resistance to almost all antibiotics,
and it has become imperative to develop novel approaches to combat its multi-drug …

Elucidating novel antibacterial compounds from the NPASS database against the FimH lectin domain for the treatment of urinary tract infections: an in-silico study

MK Al-Zrkani, RA Abdulkareem… - Journal of …, 2023 - Taylor & Francis
The increase in multidrug-resistant pathogens in urinary tract infections (UTIs) among
communities and hospitals threatens our ability to treat these common pathogens …

Gonorrhea caused due to antimicrobial-resistant bacteria Neisseria gonorrhoeae treated using probiotic peptide

G Sudhakaran, D Kesavan, M Selvam, A Arasu… - In Silico …, 2024 - Springer
Neisseria gonorrhea is a sexually transmitted disease from gonorrhea that lacks treatment;
despite the urgency, the absence of adequate drugs, lack of human correlates of protection …

In silico exploration of hypothetical proteins in Neisseria gonorrhoeae for identification of therapeutic targets

G Lakhanpal, H Tiwari, MK Shukla, D Kumar - In Silico Pharmacology, 2024 - Springer
Abstract Neisseria gonorrhoeae, a World Health Organization (WHO) declared superbug
and the second-most frequent cause of bacterial sexually transmitted infections worldwide is …

P130 Tackling antimicrobial resistance using Bioinformatics approach in superbug Neisseria gonorrhoeae by targeting Glutamate racemase (MurI)

R Kant, P Jha, M Chopra, D Saluja - 2021 - sti.bmj.com
Background Neisseria gonorrhoeae, a causative agent of gonorrhea, has developed
resistance for most of the drugs and hence recently declared as 'Superbug'. Glutamate …

Molecular docking and ADMET studies of halogenated metabolites from marine sponges as inhibitors of wild-type and mutants PBP2 in Neisseria gonorrhoeae

AR Alanzi, MF Alajmi, MJ Alqahtani - Journal of Biomolecular …, 2023 - Taylor & Francis
Gonorrhoea is a sexually transmitted infection (STI) caused by the bacteria Neisseria
gonorrhoeae. Gonorrhoea symptoms can vary, although roughly 50% of women and 10% of …

In Silico and In Vitro Evaluation of the Antimicrobial Potential of Bacillus cereus Isolated from Apis dorsata Gut against Neisseria gonorrhoeae

NJ Niode, A Adji, J Rimbing, M Tulung, M Alorabi… - Antibiotics, 2021 - mdpi.com
Antimicrobial resistance is a major public health and development concern on a global
scale. The increasing resistance of the pathogenic bacteria Neisseria gonorrhoeae to …