Osteoarthritis (OA) is a degenerative joint disease that is characterized by inflammation of
the joints, degradation of cartilage, and the remodeling of other joint tissues. Due to the …

Hyaluronic acid (HA), a biodegradable, biocompatible and non-immunogenic therapeutic
polymer is a key component of the cartilage extracellular matrix (ECM) and has been widely …

Numerous therapeutic strategies have been developed for osteoarthritis (OA) management,
including intra-articular (IA) injections. The ideal IA formulation should control cartilage …

Osteoarthritis (OA) is a serious chronic and degenerative disease that increasingly occurs in
the aged population. Its current clinical treatments are limited to symptom relief and cannot …

Hyaluronic acid (HA) is an extracellular matrix molecule with multiple physical and biological
functions found in many tissues, including cartilage. HA has been incorporated in a number …

Articular cartilage injuries have poor reparative capability and, if left untreated, may progress
to osteo-arthritis. Unsatisfactory results with conventional treatment methods have prompted …

Damage to cartilage tissues is often difficult to repair owing to chronic inflammation and a
lack of bioactive factors. Therefore, developing bioactive materials, such as hydrogels acting …

Hyaluronic acid (HA) is a natural, linear, endogenous polysaccharide that plays important
physiological and biological roles in the human body. Nowadays, among biopolymers, HA is …

Osteoarthritis (OA) is the most common type of degenerative joint disease which affects 7%
of the global population and more than 500 million people worldwide. One research frontier …

Hydrogel-based bone tissue engineering is a potential strategy for treating bone
abnormalities and fractures. Hyaluronic acid (HA) is a natural polymer that is widely …