Major roles of kupffer cells and macrophages in NAFLD development

SJ Park, J Garcia Diaz, E Um, YS Hahn - Frontiers in Endocrinology, 2023 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is an important public health problem with growing
numbers of NAFLD patients worldwide. Pathological conditions are different in each stage of …

Activation of Kupffer cells in NAFLD and NASH: Mechanisms and therapeutic interventions

GX Xu, S Wei, C Yu, SQ Zhao, WJ Yang… - Frontiers in Cell and …, 2023 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are
emerging as the leading causes of liver disease worldwide. These conditions can lead to …

[HTML][HTML] Roles of liver innate immune cells in nonalcoholic fatty liver disease

YT Zhan, W An - World journal of gastroenterology: WJG, 2010 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) has become the most common liver disease in the
United States and other developed countries and is expected to increase in the next few …

Macrophages and the development and progression of non-alcoholic fatty liver disease

B Alabdulaali, F Al-Rashed, M Al-Onaizi… - Frontiers in …, 2023 - frontiersin.org
The liver is the site of first pass metabolism, detoxifying and metabolizing blood arriving from
the hepatic portal vein and hepatic artery. It is made up of multiple cell types, including …

[HTML][HTML] Kupffer cells in non-alcoholic fatty liver disease: friend or foe?

J Chen, X Deng, Y Liu, Q Tan, G Huang… - … journal of biological …, 2020 - ncbi.nlm.nih.gov
The prevalence of non-alcoholic fatty liver disease (NAFLD) is increasing all around the
world and it may become the primary cause of terminal liver disease in adults and children …

Crucial role of T cells in NAFLD-related disease: A review and prospect

T Mao, R Yang, Y Luo, K He - Frontiers in Endocrinology, 2022 - frontiersin.org
Nonalcoholic fatty liver disease (NAFLD) includes a series of hepatic manifestations, starting
with liver steatosis and potentially evolving towards nonalcoholic steatohepatitis (NASH) …

[HTML][HTML] Role of cytokines and chemokines in non-alcoholic fatty liver disease

V Braunersreuther, GL Viviani, F Mach… - World journal of …, 2012 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) includes a variety of histological conditions
(ranging from liver steatosis and steatohepatitis, to fibrosis and hepatocarcinoma) that are …

Macrophage functional diversity in NAFLD—more than inflammation

E Barreby, P Chen, M Aouadi - Nature Reviews Endocrinology, 2022 - nature.com
Macrophages have diverse phenotypes and functions due to differences in their origin,
location and pathophysiological context. Although their main role in the liver has been …

Hepatocyte and immune cell crosstalk in non-alcoholic fatty liver disease

AM Carranza-Trejo, V Vetvicka… - Expert Review of …, 2021 - Taylor & Francis
Introduction: Nonalcoholic fatty liver disease (NAFLD) is the most widespread chronic liver
disease in the world. It can evolve into nonalcoholic steatohepatitis (NASH) where …

How inflammation impinges on NAFLD: a role for Kupffer cells

N Duarte, IC Coelho, RS Patarrão… - BioMed research …, 2015 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is rapidly becoming the most prevalent cause of
liver disease worldwide and afflicts adults and children as currently associated with obesity …